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STEP THERAPY ALGORITHMS – Formulary 2
Treatment Group
Description
Step 1: metformin

Step 2: Actoplus Met
Step 1: metformin

Step 2: Actos
Step 1: metformin

Step 2: Glyset or acarbose
Step 1: One of the following:

Step 2
: Amitiza
Step 1: One of the following atypical antipsychotics:
Step 2: Abilify or Abilify Disc or Invega or Geodon
Step 1: metformin

Step 2: Avandamet
Treatment Group
Description
Step 1: metformin

Step 2: Avandaryl
Step 1: metformin

Step 2
: Avandia
Step 1: Tier 1 or Tier 2 bisphosphonate

Step 2: Fosamax Oral Solution
Step 1: ofloxacin otic

Step 2: Cetraxal
Step 1: One of the following sulfonylurea products:
a. glyburide b. glipizide c. glimepiride
Step 2: Diabinese (chlorpropamide)
Step 1: One of the following:
b. dextroamphetamine c. dexmethylphenidate d. methylphenidate
Step 2: Strattera
Dipeptidyl Peptidase 4 Inhibitor Therapy Step 1: metformin

Step 2: Januvia or Onglyza
Dipeptidyl Peptidase 4 Inhibitor/ Metformin Step 1: metformin
Step 2: Janumet
Step 1: metformin

Step 2: Duetact
Treatment Group
Description
Step 1: One of the following atypical antipsychotics:
Step 2: Fanapt
Step 1: metformin

Step 2: Byetta
Step 1: One tier 1 or tier 2 inhaled corticosteroid
Step 2: Aerobid/Aerobid-M or Asmanex or Azmacort or Alvesco
Step 1: Singulair

Step 2: Accolate or Zyflo CR
Step 1: One of the following:

Step 2: Foradil or Serevent
Step 1: metformin

Step 2: Prandin or nateglinide
Step 1: One of the following formulary opioid products
a. hydrocodone b. hydromorphone c. methadone d. morphine e. oxycodone
Step 2: meperidine
Step 1: One of the following:

Step 2: Xalatan
Treatment Group
Description
Step 1: One of the following formulary opioid products:
c. morphine d. oxycodone e. opiate/acetaminophen
Step 2: pentazocine/ naloxone or pentazocine/ acetaminophen
Step 1: metformin

Step 2: Prandimet
Step 1: One of the following:
b. Beta-blocker c. Calcium-channel blocker
Step 2: Ranexa
Step 1: One of the following:

Step 2: Selfemra
Step 1: sumatriptan injection
Step 2
: Sumavel
Step 1: One of the following:
c. Angiotensin II receptor blocker d. Angiotensin II receptor blocker combination
Step 2: Tekturna or Tekturna HCT
Step 1: Topical Corticosteroid

Step 2: Elidel or Protopic
Treatment Group
Description
Step 1: albuterol (nebulizer)
Step 2: Xopenex Nebulizer
Step 1: allopurinol

Step 2: Uloric

*Step therapy applies to new starts only

Source: https://www.uhcretiree.com/online_documents/ovation/pdf/mapd/en/2010/Step_Therapy_Criteria.pdf

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A large case-control study of gene expression and breast cancer death in the northern california kaiser permanente population

Expression of the 21 genes in the Recurrence Score assay and prediction of clinical benefit from tamoxifen in NSABP study B-14 and chemotherapy in NSABP study B-20 Soonmyung Paik, MD 1, Steven Shak, MD 2, Gong Tang, PhD 1, Chungyeul Kim, MD 1, Heejae Joo, MD 1, Joffre Baker, PhD 2, Maureen Cronin, PhD 2, Drew Watson, PhD 2, John Bryant, PhD 1, Joe Costantino, PhD 1 and Norman Wolmark, MD

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