Okada R, Wakai K, Naito M, Morita E, Kawai S, Hamajima N, Hara M, Takashima N, Suzuki S, Takezaki T, Ohnaka K, Arisawa K, Hirohata H, Matsuo K, Mikami H, Kubo M, Tanaka H. Pro/anti-inflammatory cytokine gene polymorphisms and chronic kidney disease: a cross-sectional study. BMC Nephrol. 2012;13:2.
Hara M, Hanaoka T, MIzushima T, Honma J, Maeda K, Ohfuji S, Tanaka K, Hirota Y. Diminished immunogenicity to pandemic H1N1 2009 influenza vaccine in subjects with severe motor and intellectual disability. Vaccine 2011:29; 8323-8329.
Kanoh M, Kaneita Y, Hara M, Harada S, Gon Y, Kanamaru H, Ohida T. Longitudial study of parental smoking habits and development of asthma in early childhood. Preventive medicine (in press)
Nishida Y, iyadomi M, higaki Y, Tanaka H, Hara M, Tanaka K. influence of physical activity intensity and aerobic fitness on the anthropometric index and serum uric acid concentration in people with obesity. Intern Med 50: 2121-28, 2011.
Tsuruoka N, Iwakiri R, Hara M, Shirahama N, Sakata Y, Miyahara K, Eguchi Y, Shimoda R, Ogata S, Tsunada S, Sakata H, Fujimoto K. NSAIDs are a significant risk factor for colonic diverticular hemorrhage in elder patients: evaluation by a case-control study.J Gastroenterol Heaptol. 26(6): 1047-52. 2011.
Nanri H, Nakamura K, Hara M, Higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Tanaka K. Association between dietary pattern and serum C-reactive protein in Japanese men and women. J Epidemiol. 21(2):122-131. 2011
Nakamura K, Nanri H, Hara M, higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Tanaka K. Optimal cutoff values of waist circumference and the discriminatory performance of other anthropometric indices to detect the clustering of cardiovascular risk factors for metabolic syndrome in Japanese men and women. Environ Health Prev Med. 16:52-60. 2011.
Wakai K, et al 他 75 名（本人第 20 位）. Profile of participants and genotype distributions of 108 polymorphisms in a cross-sectional study of associations of genotypes with lifestyle and clinical factors: a project in the Japan Multi-Institutional Collaborate Cohort (J-MICC) study. J Epidemiol. 21(3): 223-235. 2011
Takashima T, Yamaguchi K, Hara M, Fukuoka T, Kuroki T, Furushima C, Wakeshima R, Iwakiri R, Fujimoto K, Inoue N. Brief Questioning by nursing staffs before endoscopic examination may not always pick up clinical symptoms of endoscopic reflux. J.Clinical. Biochem.Nutr. 46:229-233. 2010.
10. Hara M, Tanaka K, Hase T, Maeda A, Hirota Y. Evaluation of seasonal influenza vaccination effectiveness
based on antibody efficacy among the institutionalized in Japan. Vaccine; 28; 5664-5668, 2010.
11. Hara M, Higaki Y, Imaizumi T, Taguchi N, Nakamura K, Nanri H, Sakamoto T, Horita M, Shinchi K, Tanaka K.
Factors Influencing Participation Rate in a Baseline Survey of a Genetic Cohort in Japan. J Epidemiol. 20: 40-45. 2010.
12. Hara M, Inoue M, Shimazu T, Yamamoto S, Tsugane S. The association between cancer risk and age at onset of
smoking in Japanese. J Epidemiol. 20(2):128-135. 2010.
13. Matsumoto A, Ino T, Ohta M, Otani T, Hanada S, Sakuraoka A, Matsumoto A, Ichiba M, Hara M.
Enzyme-linked immunosorbent assay of nicotine metabolites. Environ Health Prev Med. 15(4):211-216. 2010
14. Yakushiji Y, Nanri Y, Hirotsu T, Nishihara M, Hara M, Nakajima J, Eriguchi M, Nishiyama M, Hara H, Node K.
Marked cerebral atrophy is correlated with kidney dysfunction in nondisabled adults. Hypertension Research. 33, 1232-1237. 2010
15. Mannen K, Tsunada S, Hara M, Yamaguchi K, Sakata Y, Fujise T, Noda T, Shimoda R, Sakata H, Ogata S,
Iwakiri S, Fujimoto K. Risk factors for complications of endoscopic submucosal dissection in gastric tumors: analysis of 478 lesions. J Gastroentero. 45:30-36. 2010.
16. Imaizumi T, Higaki Y, Hara M, Sakamoto T, Horita M, Mizuta T, Eguchi Y, Yasutake T, Ozaki I, Yamamoto K,
Onohara S, Kawazoe S, Shigematsu H, Koizumi S, Kudo S, Tanaka K. Interaction between cytochrome P450 1A2 genetic polymorphism and cigarette smoking on the risk of hepatocellular carcinoma in Japanese populations. Carcinogenesis. 30: 1729-34. 2009.
17. Otani T, Yoshii M, Kano M, Kitagawa M, Inagaki K, Kurioka N, Isomura T, Hara M, Okubo Y, Koyama H.
Validity and reliability of kano Test for Social Nicotine Dependence. Ann Epidemiol. 19: 815-22. 2009.
18. Eguchi Y., Mizuta T, Ishibashi T, Kitajima T, Oza N, Nakashita S, Hara M, Iwane S, Takahashi, H Akiyama T,
Ario K, Kawaguchi Y, Yasutake T, Iwakiri R, Ozaki I, Hisatomi A, Eguchi T, Ono N, Fujimoto K. Hepatitis C virus infection enhances insulin resistance induced by visceral fat accumulation. Liver International. 29 (2): 213-220,2009
19. Nakayama M, Iwakiri R, Hara M, Ootani H, Shimoda R, Tsunada S, Sakata H, Fujimoto K. Low-dose aspirin is
a prominent cause of bleeding ulcers in patients who underwent emergency endoscopy. J Gastroenterol 44(9):912-8,2009
20. Oura A, Ohnishi H, Hara M, Skaguchi F, Fushiki Y, Mori M. Effectiveness of influenza vaccines in reducing
risk of acute febrile illness among community-dwelling elderly, 2006-07 seasons: Population-based cohort study in Japan. The Sapporo medical Journal.78:31-37. 2009.
21. Hara M, Sakamoto T, Tanaka K Influenza vaccine effectiveness among elderly persons living in the community
during the 2003-2004 season. Vaccine 26, 6477-6480, 2008.
22. Hara M, Tanaka K, Sakamoto T, Higaki Y, Ichiba M, Horita M, Mizuta T, Eguchi Y, Yasutake T, Ozaki I, Yamamoto K,
Onohara S, Kawazoe S, Shigematsu H, Koizumi S. Case-cotrol study on cigarette smoking and risk of hepatocellular carcinoma among Japanese. Cancer Sci.99 (1):93-7, 2008.
23. Sakamoto T, Higaki Y, Hara M,, Ichiba M, Horita M, Mizuta T, Eguchi Y, Yasutake T, Ozaki I, Yamamoto K, Onohara S,
Kawazoe S, Shigematsu H, Koizumi S, Tanaka K. Interaction between interleukin-1β -31T/C gene polymorphism and drinking and smoking habits on the risk of hepatocellular carcinoma among Japanese. Cancer Lett. 271: 98-104,2008
24. Yamaguchi K, Iwakiri R, Hara M, Kikkawa A, Fujise T, Ootani H, Shimoda R, Tsunada S, Sakata H, Ushiyama
O, Koarada S, Tada Y, Nagasawa K, Fujimoto K. Reflux Esophagitis and Helicobacter pylori Infection in Patients with Scleroderma. Intern Med. 47(18): 1555-1559, 2008.
25. Yakushiji Y, Nishiyama M, Yakushiji S, Hirotsu T, Uchino A, Nakajima J, Eriguchi M, Nanri Y, Hara M,
Horikawa E, Kuroda Y. Brain microbleeds and global cognitive function in adults without neurological disorder. Stroke. 39(12): 3323-3328, 2008.
26. Tanaka K, Hara M, Sakamoto T, Higaki Y, Mizuta T, Eguchi Y, Yasutake T, Ozaki I, Yamamoto K, Onohara S, Kawazoe S,
Shigematsu H, Koizumi S. Inverse association between coffee drinking and the risk of hepatocellular carcinoma: a case-control study in Japan. Cancer Sci. 98 (2); 214-8, 2007.
27. Sakamoto T, Higaki Y, Hara M, et. al. hOGG1 Ser326Cys polymorphism and risk of hepatocellular carcinoma
among Japanese J Epidemiol.16(6):233-9. 2006
28. Hara M, Sakamoto T, Tanaka K Effectiveness of Influenza Vaccination in Preventing Influenza-like Illness
among Community-Dwelling Elderly: Population-based Cohort Study in Japan. Vaccine.24(27-28):5546-51.2006
29. Sakamoto T, Hara M, Higaki Y, Ichiba M, Horita M, Mizuta T, Eguchi Y, Yasutake T, Ozaki I, Yamamoto K,
Onohara S, Kawazoe S, Shigenmatsu H, Koizumi S, Tanaka K. Influence of alcohol consumption and gene polymorphisms of ADH2 and ALDH2 on hepatocellular carcinoma in a Japanese population. Int J Cancer. 118: 1501-1507, 2006
30. Oda K, Iwakiri R, Hara M, et. al. Dysphagia associated with gastroesophageal reflux disease is improved by
proton pump inhibitor. Digestive Diseases and Science. 50 (10): n1921-26, 2005.
31. Hara M, Tanaka K, Hirota Y. Immune response to influenza vaccine in healthy adults and the elderly:
association with nutritional. Vaccine. 23: 1457-63, 2005
32. Tsukino H, Hanaoka Y, Otani T, Iwasaki M, Kobayashi M, Hara M, Natsukawa S, Shaura K, Koizumi Y,
Kashuga Y, Tsugane S. hOGG1 Ser326Cys polymorphism, interaction with environmental exposures, and gastric cancer risk in Japanese populations. Cancer Science. 95(12): 977-83, 2004.
33. Hara M, Hanaoka T, Kobayashi M, Otani T, Adachi HY, Montani A, Natsukawa S, Shaura K, Koizumi Y,
Kasuga Y, Matsuzawa T, Ikekawa T, Sasaki S, Tsugane S. Cruciferous Vegetables, Mushrooms, and Gastrointestinal Cancer Risks in a Multi-center, Hospital-based Case Control Study in Japan. Nutr Cancer.
34. Matsunaga K, Iwakiri R, Hara M, Sakata H, Ogusu T, Shimoda R, Oda K, Utsumi H, Yamamoto K, Fujimoto K.
Endoscopic injection sclerotherapy for esophageal varices in cirrhotic patients with hepatocellular carcinoma: risk factors for survival. J Clin Gastroenterol. 36(1): 68-71, 2003.
35. Nishimura S, Zaitsu M, Hara M, Yokota G, Watanabe M, Ueda Y, Imayoshi M, Ishii E, Tasaki H, Hamasaki Y. A
polymorphism in the promoter of the CD14 gene (CD14/-159) is associated with the development of coronary artery lesions in patients with Kawasaki disease. J Pediatr. 143(3):357-62; 2003.
36. Okamoto K, Iwakiri R, Mori M, Hara M, Oda K, Danjo A, Ootani A, Sakata H, Fujimoto K. Clinical Symptoms
endoscopic reflux esophagitis: evaluation in 8031 adult subjects. Digestive Diseases and Sciences. 48 (12): 2237-41; 2003
37. Hara M, Sobue T, Sasaki S, Tsugane S. Smoking and Risk of Premature Death among Middle-aged Japanese:
Ten-year Follow-up of the Japan Public Health Center-based Prospective Study on Cancer and Cardiovascular Diseases (JPHC Study) Cohort I. Jpn J Cancer Res. 93: 6-14, 2002.
38. Hara M, Sasaki S, Yamamoto S, Sobue T, Tsugane S. Comparison of cause-specific mortality between
respondents and nonrespondents in a population-based prospective study: ten-year follow-up of JPHC Study Cohort I. J. Clin. Epidemiol. 55: 150-156, 2002.
39. Sobue T, Yamamoto S, Hara M, Sasazuki S, Sasaki S, Tsugane S: Cigarette smoking and subsequent risk of
lung cancer by histologic type in middle-aged Japanese men and women: the JPHC study. Int J Cancer. 99(2):245-51, 2002.
40. Hara M, Mori, Hara T, Yamamoto K, Hond M, Nishizumi M: Risk of developing hepatocellular carcinoma
according to the titer of antibody to hepatitis C virus. Hepato-Gastroenterology. 48: 498-501, 2001.
41. Mori M, Hara M, Wada I, Hara T, Yamamoto K, Honda M, Naramoto J: Prospective study of hepatitis B and
C viral infections, cigarette smoking, alcohol consumption, and other factors associated with hepatocellular carcinoma risk in Japan. Am J Epidemiol 15; 151(2): 131-139, 2000.
42. Hara M, Mori M, Shono N, Higaki Y and Nishizumi M: Lifestyle-related risk factors for total and cancer
mortality in men and women. Environ Health Preventive Med 55(3): 90-96, 2000.
43. Hara M, Mori M, Shono N, Higaki Y and Nishizumi M.:Body mass index and risk of cancer in men and
44. Hara M, Mori M, Nishizumi M: Difference in lifestyle-related risk factors for death by occupational group;
a prospective study. J Occup Health 41:137-143, 1999.
桧垣靖樹、森満、原めぐみ、庄野菜穂子、甲斐今日子、中原由美、西住昌裕. 市民の日常生活状況と健康度に関する研究.厚生の指標.45(8):21-26.1998.
原 めぐみ, 花岡 知之. 長野県の低がん死亡率と農作物との関連についての疫学研究. 農工研通信 129 (1): 2-6,2004.
Hara M, Sasaki S, Tsugane S: Effect of smoking on the association between alcohol consumption and cancer mortality among middle-aged Japanese men: JPHC Study Cohort I. IARC Scientific Publication Book No.156: 165-168, 2002.
和文 1. 原 めぐみ. インフルエンザワクチンって本当に効くの？チャイルドヘルス. 14（10）: 31-35. 2011
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It is with gratitude and a sense of accomplishment that I announce the debut of the new www.KamalaHealth.com webpage. While the old one represented the support of a community of instructors that helped me grow into the therapist I am today, the new one represents the direction of the business. Thanks to the real clients who posed for treatment pictures, and my friend who patiently worked