Better Health with
XANGOTM Mangosteen Juice
REASONS PEOPLE TAKE XANGO
MANGOSTEEN JUICE . 3
MANGOSTEEN JUICE SHOULD I
DRINK A DAY? . 8
Is XanGo MANGOSTEEN Juice
just another hyped up health fad?
View the research at the National Library of Medicine:
XANGOtm MANGOSTEEN JUICE
The Xanthones found in the Mangosteen fruit are listed with 138 separate health benefits which have
been condensed to the following list:
1. Anti-fatigue 2. Anti-tumor and cancer prevention - multiple categories cited 3. Anti-aging 4. Hypotensive - blood pressure lowering 5. Hypoglycemic - blood sugar lowering (anti-diabetic effect) 6. Immuno-stimulant - multiple categories cited 7. Anti-lipidemic - blood fat lowering 8. Anti-oxidant 9. Anti-obesity - helps with weight loss10. Anti-atheroscierotic - prevents hardening of the arteries11. Cardio-protective - protects the heart12.Anti-viral - prevents or modulates viral infections13.Anti-biotic - prevents or modulates bacterial infections14.Anti-fungal - prevents or modulates fungal infections15.Anti-depressant16. Anxyolytic - anti-anxiety effect17. Anti-Alzeheimerian - helps prevent dementia18. Anti-arthritic - prevention of arthritis19. Anti-osteoporosis - helps prevent the loss of bone mass20. Anti-periodontic - prevents gum disease21. Anti-allergenic - prevents allergic reaction22. Anti-seborrhic - prevents seborrhea (skin disease that causes dandruff, for example)23. Anti-caluculitic - prevents kidney stones24. Anti-pyretic - fever lowering25. Anti-Parkinson26. Anti-diarrheal27. Anti-neuralgic - reduces nerve pain (i.e. Diabetic neuropathy of feet or hands)28. Anti-vertigo - prevents dizziness29. Anti-glaucomic - prevents glaucoma30. Anti-cateract - prevents cataracts
Migraines, Analgesic - prevents pain, anti-inflammatory prevents inflammation, Anti-ulcer, prevents both
stomach, mouth and bowel ulcers. The most powerful Antioxidant on the market.
Interferes with HIV protease, diverticulosis, reduces excess stomach acid, relevant for asthma, acne,
impetigo, dermatitis, eczema, skin cancer and sun damage.
Pain and swelling are a result of inflammation caused by Prostaglandins (made from COX-2 enzyme) that
are sent to the area of injury to help protect it from further injury. Sometimes the inflammation results in
high fevers, drop in blood pressure, coma or even death. Other times the inflammation remains at a low
level, resulting in chronic pain. The Mangosteen stops inflammation by inhibiting the COX-2 enzyme
XANGOtm MANGOSTEEN JUICE
Reasons People Take XanGo Mangosteen Juice
The full list of potential benefits you can experience when drinking XANGO Mangosteen Juice, is long.
Scientific research on the mangosteen fruit by a number of experts indicates that it can have well over 100
positive effects. We offer here a partial list of topics that describe some of the potential benefits of drinking
XanGo Mangosteen Juice.
The World Bank has a think tank of experts who each year consider all of the world’s serious challengesand Prioritize them. In 2002, these experts felt that the integrity of the world’s water supply was the earth’stop problem. However, the number two spot was taken by the problem of bacterial resistance to antibiotics.
Studies show that xanthones inhibit the production of the bacteria. Other experiments have shown thatsalmonella typhi and the tuberculosis bacteria are also destroyed by mangosteen xanthones.
Systemic fungal infections have increased 800 percent in the past decade, and in those patients the mortalityrate is from 40 - 60 percent. The xanthones of the mangosteen were tested experimentally against threecommon fungi and were proven capable of effectively inhibiting their growth
To combat the destructive effect of free radicals upon cells, “antioxidants” are necessary in large quantities.
An antioxidant is an atom or molecule with extra electrons it can donate to inactivate or “mop up” freeradicals. After studying the antioxidant properties of the mangosteen, a new laboratory test known asORAC (Oxygen Radical Absorbency Capacity), developed by USDA researchers at Tufts University, ratesXANGO Mangosteen Juice as the number one antioxidant food on the market. Researchers discovered thatthe rind exhibited “potent free radicals scavenging activity.”
Cancer always begins with a single change in a single cell. Every day the immune system literally “snuffsout” numerous aberrant cells that could become cancerous. The anti-cancer activity of phytoceuticals hasbeen well documented. Catechins, tannin derivatives, found in many plants and in high amounts inmangosteen, have been shown to protect from cancer in at least three different ways:
1) Prevent the formation of carcinogenic compounds by blocking co-carcinogens.
2) Turn up the body’s natural detoxification defenses.
3) Directly suppress cancer promotion or growth.
Mangosteen should work well with all cancer treatments and will provide its benefits without the necessityof stopping other therapies.
Viruses account for the majority of human infections, many of which are acute short-lived illnesses likecolds. Other viruses are never eliminated from the body but persist for years in chronic infections. Becausexanthones have anti-viral capabilities, scientists at the National University of Singapore investigated theeffects the mangosteen xanthones would have on the HIV virus. In the experiment, two xanthonesdemonstrated the ability to interfere with HIV protease causing the virus to remain immature and incapableof infection.
XANGOtm MANGOSTEEN JUICE
Asthma is a chronic (long duration) inflammatory disease of the smaller airways of the lungs. Manyelements of the immune system are activated in an asthma attack, but they are part of the problem ratherthan part of the solution in this widespread disease. In asthma, inflammation and other complex immunesystem effects cause recurrent episodes characteristic wheezing when the small airways of the lungs arenarrowed due to the contraction of the muscle walls. Asthma can develop at any age but about 50 percent ofcases occur in childhood. The majority of the remaining cases start before age 40. It is rare to developasthma after age 50. The incidence of the disease has been increasing and despite the development of manynew medications, the number of deaths from asthma has risen substantially in recent years. Unfortunately,all the medications used to treat asthma have nasty or dangerous side effects. Bronchodilaton cause rapidbeating of the heart and can precipitate panic attacks. Steroids, inhaled and oral, have side-effect profilesthat literally fill several pages in texts dealing with the administration and surveillance of medicines.
Mangosteen xanthones are powerful anti-inflammatory. They have antiviral qualities that can lead to areduction in the number of viral infections in humans. They are very potent antioxidants and help tocounteract the free radical damage of air pollution, and finally, they have been shown to have anti-allergyeffects.
In this topic, we discuss type II diabetes, also known as non-insulin dependent, or adult-onset diabetes.
Diabetes is a metabolic disease, and this description deserves an explanation. Metabolism refers to virtuallyall of the chemical processes involved in maintaining life,. Digestion of food, tissue maintenance and repairand energy production are only three of the major elements, but they are the metabolic functions mostaffected by diabetes. Diabetes is due to insufficient insulin to open the cell doors to glucose. Even thoughtype II diabetics produce more insulin that a normal person would need, at least early in the disease, theystill do not have enough insulin. They have a relative deficiency of insulin. Glucose doesn’t enter the cellin sufficient amounts, and its levels rise in the blood. If the only defect in diabetes was the inability to getenough glucose into cells, it would be bad enough, but that is only half the problem. High blood glucoselevels are extremely toxic. Directly and indirectly, they cause numerous serious problems. Patients usingmangosteen supplement report:
1) Decreased fasting blood-sugar levels.
2) Decreased 2-hour, postprandial blood-sugar levels.
3) Improved energy levels4) Decreased appetite and even weight loss.
5) Decreased requirements for hypoglycemic medications.
6) Decreased pain from neuropathy.
Crohns’s disease is another chronic inflammatory disease with no identified cause, which commonly afflictsyoung people from 10 to 30 years of age. Initially, it may appear to be ulcerative colitis, however, themasquerade usually ends when this terrible disease manifests its ability to appear anywhere along the entireGI tract form mouth to anus.
Generally, more debilitating than ulcerative colitis, Crohns’s disease is often treated surgically by resectingareas of diseased bowel, which never fully heal and where scarring can cause obstruction. Crohns’s diseasebegins below the mucosa and spreads both inward and outward through the deeper layers of the bowel wall.
Once again, the mainstay of medical treatment is the use of powerful anti-inflammatory medications (likesteroids). However, since most cases of Crohn’s involve the small bowel, medications are oral, and theirside effects are systemic (affecting the whole body). As with ulcerative colitis, the mangosteen addressesthe problems of inflammation, immune cell damage, and the threat of infection in Crohn’s disease.
Diverticulosis is a condition where small outpouchings of bowel mucosa protrude through the outer
XANGOtm MANGOSTEEN JUICE
muscular layers of the large bowel wall. When these tiny sacs become inflamed, the condition is calleddiverticulitis. The disease occurs almost exclusively in the elderly and is far more common in societies likethe US. where the average diet lacks sufficient fiber. Mangosteen preparations where the whole fruit ispureed should be strained by anyone with a history of diverticulitis. However, the benefits are worth theextra effort as the anti-inflammatory and the anti-microbial effects of the mangosteen decrease thefrequency of attacks. Perhaps the most widespread use of the mangosteen for folk medicine purposes hashad to do with the gastro-intestinal (GI) system. Dysentery in the third world has at times reached plagueproportions and is always a significant factor in the mortality of infants and children. Active against GIpathogens, the mangosteen is also used to reduce the inflammation in the intestine, which causes the loss ofessential nutrients and body fluids into the stool. In other GI related studies a laboratory in 1996demonstrated that the xanthones, alpha and gamma mangostin, had both histamine and serotonin receptorblocking capacity.
The world around us contains all sorts of microbial dangers. Daily, we are confronted with bacteria,viruses, fungi and parasites. These organisms are called pathogens, and they invade our bodies at everyopportunity. Our body’s immune system miraculously orchestrates a complex defense system againstpathogenic invaders. However, the immune system is weak at various times in our life, like in infancy andold age, and is affected by nutrition, pollution and many other environmental factors such as the radiationfound in sunlight. That is why diet, exercise and supplements, to support and bolster the immune system,play critical roles in keeping our bodies healthy and strong.
While inflammation can affect all tissues in the body, it is the primary mechanism underpinning diseaseswhich attack muscles, joints and connective tissue. Researchers from India used the rind from mangosteento investigate its effect on other types of inflammation in the body. Their experiments produced thefollowing results:
1) Suppression of acute and chronic inflammation and edema in rats.
2) Inhibition of systemic anaphylaxis (fatal inflammatory reaction
) in guinea pigs and rats.
3) Inhibition of arthritis in rats.
In another paper studying mangosteen’s effect on inflammation, it was noted that the xanthones do notinterfere with the clotting mechanism of blood or produce stomach ulcers. Both of these are serious sideeffects of anti-inflammatory drugs. In fact, it was found that the xanthones exhibited significant anti-ulceractivity in experimental animals.
The mangosteen contains xanthones that are among the most potent antioxidants known to science.
Research has demonstrated that positive effect these xanthones can have in preventing atherosclerosis. Thecardiovascular system consists of the heart that pumps oxygen-rich blood via arteries to every cell in thebody, and the veins and capillaries that eventually bring it back to the heart. According to the AmericanHeart Association (AHA), in 1999 cardiovascular disease contributed to one-third of all global deaths. TheAHA has estimated that by 2010 cardiovascular, disease will be the leading cause of death in developingcountries.
Cancer is a blanket term covering a variety of disorders with the common element of abnormal,uncontrolled cell growth that will not stop on its own. Under normal conditions, cell growth is strictlycontrolled with cell birth equaling cell death so that the total number of cells in the body remains relativelyconstant. A prominent free radical researcher, Dr. Bruce Ames, estimates that the DNA material in everyone of the trillions of cells in our body receives about ten thousand hits from free radicals everyday! To
XANGOtm MANGOSTEEN JUICE
prevent a breach of the body’s defenses in the face of an attack of such magnitude requires the concertedefforts of all the agents of the immune system, which can be seen as the armed forces of the body, alongwith the collaboration of the policemen or the gene regulatory mechanism. Mangosteen’s xanthones(phytoceuticals found only in this plant) have proven ability to destroy cancerous cells, and in fact,Garcinone E, a xanthone, was more effective than five commonly used chemotherapy agents for stomach,lung and liver cancer vincristine, mitoxantrone, 5-fiourouracil, cisplastin and methotrexate) in a recent well-designed in vitro study. Where do the mangosteen phytoceuticals intervene in this deadly process? Well,the answer is that in addition to being anti-tumor agents when cancer already exists, they prevent and arrestcancerous change at every step. Finally, while it is exciting to realize what the mangosteen phytoceuticalswill do in the area of cancer treatment, it is more important to prevent the development of cancer in the firstplace. Nothing does it better than mangosteen.
Scientists from Australia and Thailand have postulated that if mangosteen inhibits oxidative (free radical)damage, then perhaps it could help with reducing the oxidation of LDL (“bad” cholesterol) in the blood.
After a series of such experiments, the scientists concluded that the xanthones from mangosteen areeffective inhibitors of LDL oxidation. They further suggested that the xanthones possess therapeuticpotential. Several other studies show that polyphenois, also found in the mangosteen, were discovered to befive times more potent as antioxidants that vitamin C, which is commonly regarded as the most powerfulknown antioxidant. Our bodies are composed of trillions of cells, and the death, mutation or destruction ofeven millions of cells may not be noticeable to the victim in whose body it is occurring. However, a heartattack or stroke doesn’t occur out of the blue. Before such deadly events are manifest, years of cellularwarfare have been going on within the body, and the only evidence of the struggle may have been a simplelack of energy or the loss of a sense of well being.
Few diseases have been in the public eye as consistently as Parkinson’s and Alzheimer’s. These terriblydebilitating degenerative diseases of the central nervous system already affect millions, and the incidence isrising yearly. Unfortunately, the emphasis in research has been of finding cures rather than focusing onprevention. Once again, Dr. Nakatani’s research with glial cells (central nervous system cells) suggests thatmangosteen could produce a therapeutic effect in both the prevention and treatment of Parkinson’s andAlzheimer’s disease by reducing oxidative damage and inflammation.
Chronic Obstructive Pulmonary Disease
COPD is the acronym for chronic obstructive pulmonary disease, a label grouping two common obstructivelung diseases: emphysema and chronic bronchitis. Caused by smoking, air pollution and occupationalexposure, these two entities commonly coexist population over the past couple of decades. Currently, itaffects about 15 million people and is the fourth leading cause of death in the U.S. Chronic bronchitis isdefined as chronic cough productive of mucous for at least three months of the year and for at least twoyears. In emphysema, the obstructive component of the disease results from changes in lung tissue ratherthan from the increased production of mucous or the presence of chronic inflammation as in chronicbronchitis. Once again, as it does in asthma, mangosteen intervenes at several points in the diseaseprocesses of chronic bronchitis and emphysema. Its antiviral, antibacterial and anti fungal effects canreduce the frequency of lung infections, thereby reducing cumulative tissue damage. As a result, fewercourses if antibiotic therapy are required. The anti-inflammatory effects of the xanthones (active biologicalingredients in the mangosteen) decrease both inflammation and cell damage while helping prevent the onsetof deadly pulmonary hypertension. Since mangosteen extract also has potent antioxidant effects, itintervenes in every process where free radicals cause cell damage, whether from the inflammation ofchronic bronchitis or the destruction of the elastic recoil of the alveoli in emphysema.
XANGOtm MANGOSTEEN JUICE
Multiple Sclerosis is the leading cause of neurological disability in young adults. It usually strikes between20 and 50 years of age with a peak of age 30, and women are afflicted twice as often as men. The centralnervous system, meaning the brain and the spinal cord, is the target of this disease, which is bothinflammatory and auto-immune in nature. Other diseases, which belong to auto-immune category, arerheumatoid arthritis, some forms of hypothyroidism and lupus. While the absolute cause of MS is still notclear, more than 20 infectious agents, both viruses and bacteria, have been linked to its occurrence. TheXanthones of mangosteen are powerful anti-inflammatory and appear to work by diminishing the damage ofinflammation both during and between attacks. Additionally, experiments, with powerful antioxidanttherapy have shown protective effects upon the myelin sheaths when they are attacked by the immunesystem. Macrophages, using bunts of free radicals to damage myelin, are major contributors to thepathology of MS, and mangosteen extract has potent antioxidant effects. Finally, the anti-microbialprotection of mangosteen can prevent the initial infections that lead to MS as well as prevents recurrenturinary tract and bedsore infections in patients with advanced disease.
Myalgia simply means muscle pain, and there are literally a dozen disease entities as well as just plainunaccustomed exertion that can cause it. Once severe destruction of the muscle fibers has been ruled out byblood tests, the problem becomes the control of the inflammation that’s causing pain. Non-steroidal anti-inflammatory drugs, NSAIDS, are used both across the counter and by prescription to control symptoms.
However, these drugs have nasty side effects, and if used for a prolonged period of time, they can causestomach irritation, ulcers, gastro-esophageal reflux and kidney damage. This is true even of the newer(Cox2) drugs, like Vioxx, Celebrex and Bextra. Even though the danger of stomach problems is less withthe Cox2 drugs, the kidney problems are the same as with the older preparations, like ibuprofen, Naproxenand so forth. It makes sense to use side effect-free alternatives. In laboratory studies, mangosteen extractwas found to be a more potent anti-inflammatory agent than the Indomethacin or Dexamethasone, and isvery effective in the treatment of myalgia. Additionally, it has been found to have helicon pyloriantibacterial effect and was observed to heal ulcers in laboratory animals.
As air pollution increases, the incidence of asthma, an allergic inflammatory disease of the lungs, is risingalarmingly. Both TB and asthma, including all other forms of lung infections, begin with the inhalation ofmicrobes or allergens. A study released in September of 2002 reported that the rind of the mangosteen notonly acted as an anti-inflammatory agent but also as an anti-allergenic agent. This is important informationfor asthma sufferers. When you consider that the mangosteen affects both the initial insult and the body’sinflammatory response to asthma, it becomes a unique agent in the treatment of the disease. No other singleagent can intervene in both disease pathways. Mangosteen alone can be predicted to accomplish what wenow use several drugs to do in the treatment of asthma
Skin disorders are usually problems of inflammation, like eczema and dermatitis; infection, like wounds,ringworm, acne and impetigo; and growth disorders of the dermis, like psoriasis or seborrhea. Cancer andsun damage make up the remaining common causes of skin complaints. Mangosteen has once again beenused in folk medicine for centuries to treat these problems.
Hormones are made in the hypothalamus, Pituitary, thyroid, adrenal pancreas and sexual organs. Theseglands can not produce the correct levels of hormones if they are stressed by free radicals and infection.
Mangosteen helps by fighting off infection, helps promote better blood flow that make transporting the
XANGOtm MANGOSTEEN JUICE
hormones to all parts of the body effectively. High cortisol levels causes hypogonadism (inability of testesto produce enough testosterone) cirrhosis of the liver, lipid abnormalities, obesity, prostate cancer, andemotional disturbances. Estradol, progesterone and testosterone imbalance, negatively affects a woman’smenstrual cycle, sleep patterns, libido, mood swings and PMS symptoms. Imbalance of cortisol, the stresshormone are associated with obesity, depression, chronic fatigue and other health problems. Women needmangosteen xanthones to help balance their hormone levels. High cortisol levels that deplete hormonelevels reduces possible fertility.
How Much XanGo Mangosteen Juice Should I Drink a Day?
“No adverse affects, apart from minor allergic skin reactions, were encountered and no supplement-drug
interactions where noted in our clinical experience. Dosages are flexible and, since no toxic level exist,
large doses are not dangerous. I would suggest, however, that multiple smaller doses (up to three times
daily)are preferable to a single large daily dose. Benefits can be expected at even minimal daily amounts
(i.e. one ounce - two table spoons) but serious or chronic conditions may require up to eight ounces daily.
Titration or the incremental increase of dosage, over several weeks will help determine how much is needed
for acceptable effects in any individual consumer. As a rule of thumb, those people using the XanGo
Mangosteen Juice to treat existing illness should take 1 to 2 oz (1 to 4 tablespoons) before meals up to three
times daily. Taking the XANGO Mangosteen Juice before meals will ensure better digestion and absorption
of it. Phytochemicals. People seeking to use the XANGO Mangosteen Juice for prevention only will be
well served by a single 1oz. daily. Mangosteen provides powerful protection for every organ system in the
human body. This fact is being confirmed on a daily basis by clinical experience. I am convinced that
Mangosteen will, without a doubt, be the most successful food supplement ever. In conclusion, I restate my
firm belief that you will have difficulty realizing all the health benefits you will receive form using the
XANGO Mangos teen Juice”
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*Customers and/or Distributors have a 30-day, 100% satisfaction guarantee with their initial purchase (Thefirst order, going to a single address, placed within thirty (30) days of the Distributor application. Often, butnot necessarily, placed at the time of application). The Company will refund the net purchase price (lessshipping charges), or replace product, of any initial product order, up to two cases, to customers and/orDistributors who are in any way dissatisfied with their product. In order to receive this refund, customersand/or distributors must call the Customer Service Department within 30 days of purchasing the initial orderand request an RMA number. Initial orders of two cases or less do not need to be returned to the Company.
If a Customer order is returned in re-saleable condition to the Company within seven (7) days by a traceablemeans of delivery. Upon receipt, the return will be noted and a refund will be issued within 30 days.
Health Benefits of Tennis Babette M Pluim (1), J Bart Staal (2), Bonita L Marks (3), Stuart Miller (4), Dave Miley (4) (1) Royal Netherlands Lawn Tennis Association (KNLTB), Amersfoort, The Netherlands (2) Department of Epidemiology and Caphri Research Institute, Maastricht University, Maastricht, The (3) Department of Exercise and Sport Science, University of North Carolina at Chap
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