Bericht phytohormone-en.indd

Literature overview of Dr. Wolff R&D on experiences with alternative phytohormone replacement therapy for menopausal problems.
Phytofl avonoids in menopause and thereafter e phase of hormonal change in women during menopause is diffi with both physically and psychologically. Th begins around age 40 to 45, reveals the extremely complicated scope of action of the hormone estrogen and its derivatives. Apart from vegetative disorders and the well-known heat fl ashes and sweats, there are cardiovascular changes, an increase in bone porosity as well as changes in the skin‘s appearance or regene- For a long time, replacement of the missing estrogens by external administra- tion of these hormones seemed the suitable means for eliminating the above- mentioned problems. However, the benefi t of hormone replacement therapy has been an item of controversy for several years, since women who receive external estrogen are subject to an increased risk of breast and uterine cancer. A recently completed study of the Women‘s Health Initiative (WHI) also ascertained a slightly increased breast cancer risk for classic hormone replacement therapy. Due to this experience, physicians are a little more careful today and carefully weigh the benefi ts and potential risks of hormone replacement therapy.
A natural alternative to hormone replacement therapy can be found in various plants. A statistical comparison of the breast cancer risk in Asian and Euro- pean women has revealed that there are signifi cantly fewer cases in Asia than in is surprising result could be connected to the very high consumption of soy-containing foodstuff s in Asia. Th called secondary botanical active ingredients (genistein) that are able to develop Soy (Glycine soja), plant and fruit, a weak estrogen eff ect. Black cohosh (Cimicifuga racemosa) also contains such As a matter of fact, it was demonstrated that women‘s menopausal problems decreased based on the application of soy products. No such undesirable risks as in estrogen replacement therapy were detected so far. Th surprise, if one considers the widespread availability of soy as a foodstuff .
Genistein and cimicifugin are very eff ective phytoestrogens. Th cacy includes the most important areas of antiandrogen properties such as a reduction in skin aging, bone porosity, cardiovascular improvement, antidiabetic properties and the antiandrogen protective functions in the hair root.
Black cohosh (Cimicifuga racemosa), Literature overview of Dr. Wolff R&D on experiences with alternative phytohormone replacement therapy for menopausal problems.
White tea (Camelia sinensis) is also a valuable source of activating botanical ingredients. Phytofl avones, polyphenols and trimethylxanthines such as caff eine complement the antiandrogen active profi le with a pronounced antiradical and cell membrane stabilization properties. When it comes to the tea plant, Asia can also look back on long-standing experience with phytotherapy, so that effi and tolerability are also guaranteed in this respect.
Also within the hair roots, the antiandrogen eff ect of the phytofl avones helps strengthen their resistance and improve the energy supply. In doing so, they sup- plant and blossom, chemical structure port the hair roots‘ growth and regeneration. Menopausal women who measure their waning estrogen-based protection by the number of lost hairs, can fi ght this hair loss eff ectively and sustainably with phytoestrogen-based active ingredients, ey will maintain their hair in a healthy and vigo- For further information, please visit www.plantur39.com.
Expert terminology marked in green is explained in the glossary.
Literature:
Rohr D.; Soja und Rotklee, Phytoestrogene in der Prävention
Privatdozent Dr. Dr. Uwe D. Rohr
Abteilung für Gynäkologische Endokrinologie und Sterilitätsbehandlung, Medizinische Universität Wien, AKH www.pharmazeutische-zeitung.de/pza/2004-45/titel.htm Osmers R., Kraft K.;
Phytotherapie bei Wechseljahresbeschwerden: Stand der Forschung
Rüdiger Osmers, Prof. Dr. med. 1), Karin Kraft , Prof. Dr. med. 2)
1) Fachabteilung Frauenheilkunde, Städt. Krankenhaus Hildesheim 2) Moorbadklinik Bad Doberan, Schwaaner Chaussee 2, 18209 Bad DoberanPharmazie in unserer Zeit, Volume 33, Issue 5 , Pages 384-391, 2004 Günter Vollmer, Prof. Dr. rer. nat., Oliver Zierau, Dr. med. vet.;
Was sind Phytoestrogene und Phyto-SERMs?: Pfl anzeninhaltsstoff e mit Wirkung auf das Hormonsystem
Molekulare Zellphysiologie und Endokrinologie, Institut für Zoologie,
Technische Universität Dresden, Mommsenstr. 13, 01062 Dresden
Pharmazie in unserer Zeit, Volume 33, Issue 5 , Pages 378 - 383, 2004
Zeit des Wandelns, Wechseljahre ohne Hormontherapie, „Regellose“ Frauen, Erfahrungsheilkunde 2004;
53: 542-549
Wuttke W, Seidlova-Wuttke D, Gorkow C;
Th
e Cimicifuga preparation BNO 1055 vs. conjugated estrogens in a double-blind placebo-controlled study:
eff ects on menopause symptoms and bone markers.
Maturitas. 2003 Mar 14;44 Suppl 1:S67-77
M.Schmidt, W. Polasek, R.Käuferler;
Wirksamkeit und Sicherheit von Cimicifuga racemosa bei Menopausebeschwerden
Journal für Menopause, 1005 12(1), 27-32
McKee J; Warber SL, Integrative therapies for menopause.;
Southern medical journal; VOL: 98 (3); p. 319-26
Beck V; Unterrieder E; Krenn L; Kubelka W; Jungbauer A;
Comparison of hormonal activity (estrogen, androgen and progestin) of standardized plant extracts for large
scale use in hormone replacement therapy.
e Journal of steroid biochemistry and molecular biology; VOL: 84 (2-3); p. 259-68 Shaw JC; Green tea polyphenols may be useful in the treatment of androgen-mediated skin disorders.
Archives of dermatology; VOL: 137 (5); p. 664 Liao S; Hiipakka RA;
Selective inhibition of steroid 5 alpha-reductase isozymes by tea epicatechin-3-gallate and
epigallocatechin-3-gallate.
Biochemical and biophysical research communications; VOL: 214 (3); p. 833-8

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