Risk Assessment Tool for the use of MRSA suppression therapy in Primary Care. Staphylococcus aureus is a common coloniser of human skin and mucosa, but can cause disease, particularly if there is an opportunity for the bacteria to enter the body. Meticillin-resistant S. aureus (MRSA) are a type of S. aureus resistant to antibiotics such as Flucloxacillin that are normally used to treat S. aureus infections. Most patients who are colonised with MRSA do not go on to develop an infection, but colonisation is a known risk factor. A systematic review found that MRSA colonisation was associated with a four-fold increased risk of infection compared with MSSA (Meticillin-sensitive S. aureus)colonisation1 . MRSA is not confined to a hospital setting. MRSA infected patients who are discharged from hospital may continue to carry MRSA even after their infection has resolved. Similarly patients may become colonised with MRSA during a hospital stay, a condition that may persist after discharge.2 Overall there has been a 59% decrease in the number of MRSA (bacteraemia) episodes reported during the surveillance period in England between October 2007 & December 2009. Across all patients, the average age ranges from 65 to 71 years3. In Cornwall significant work has been undertaken to review the risk factors involved in cases of MRSA bacteraemia. A risk assessment tool was developed for use with patients on the district nursing caseload. Patients with a number of risk factors were offered screening and, if positive, suppression therapy. The tool below has adapted the same risk factors but altered the perspective to allow risk assessment of known positive patients to inform the decision to offer suppression therapy. Mupirocin resistance is associated with exposure to Mupirocin in the previous year4 and therefore prescription of suppression therapy should follow risk assessment.
Safdar N, Bradley EA. The risk of infection after nasal colonization with Staphylococcus aureus. Am J Med 2008;121:310–315
International Scientific Forum on Home Hygiene, 2006
Health Protection Agency Quarterly Surveillance report. June 2010.
., . Risk factors associated with mupirocin resistance in meticillin-resistant Staphylococcus aureus. Journal of Hospital Infection. Nov;76(3):206-10. Epub 2010 Sep 16.
Lisa Johnson Nurse Consultant DIPC May 2011
RISK ASSESMENT WHEN MRSA POSITIVE RESULT RECEIVED
Refer to MRSA information in prescribing guidelines for future antimicrobial prescribing.
Conduct this risk assessment even for known positive patients unless recent risk assessment noted on file. Yes – Prescribe suppression and repeat screening if required by Q1) Is the patient the admitting team. booked for No – go to Q2
Suppression is indicated for the 5 days leading up to
Q2) Is the patient
The rationale is to reduce risk of transmission to other
inpatients and reduce risk of infection to the positive
patient by suppressing carriage prior to admission.
Suppression should have been supplied/prescribed by the
Prescribe suppression if none supplied (Covered by
No – go to Q3 Q3) Is the patient
Risk assessment should already be complete.
Suppression prescription may be requested by nurse
No – review risk factors below
Lisa Johnson Nurse Consultant DIPC May 2011
MRSA positive Patients with 4 or more risk factors should be considered for suppression.
Discussion with a Microbiologist or Infection Prevention Nurse Consultant may be necessary.
Microbiology Acute settings Community Settings
Lead Nurse Cornwall Community Health Services (DNs, Podiatry, Community
Lisa Johnson Nurse Consultant DIPC May 2011
Recommended Clothing & Equipment List The following list is designed to get you oriented to the activities planned for your trip with Explore Bolivia and the appropriate clothing and equipment you will need. Just the essentials are necessary, so try to pack minimally. We provide all the camping equipment, except sleeping bags and pads. You will need to bring along some basic essenti
Thorax Online First, published on September 15, 2011 as 10.1136/thoraxjnl-2011-200017 Identification of FGF7 as a novel susceptibility locusfor chronic obstructive pulmonary diseaseJohn M Brehm,1 Koichi Hagiwara,2 Yohannes Tesfaigzi,3 Shannon Bruse,3Thomas J Mariani,4 Soumyaroop Bhattacharya,4 Nadia Boutaoui,1 John P Ziniti,5Manuel E Soto-Quiros,6 Lydiana Avila,6 Michael H Cho,5,7,8 Blanca Him