Es ist nicht klar, wie groß die Rolle von Antibiotika https://antibiotika-wiki.de/ in den Wettbewerbsbeziehungen zwischen Mikroorganismen unter natürlichen Bedingungen ist. Zelman vaxman glaubte, dass diese Rolle minimal ist, Antibiotika werden nicht anders als in reinen Kulturen auf reichen Umgebungen gebildet. Anschließend wurde jedoch festgestellt, dass bei vielen Produzenten die Aktivität der antibiotikasynthese in Gegenwart anderer Arten oder spezifischer Produkte Ihres Stoffwechsels zunimmt.
Microsoft word - prostate hope clinical observation.doc
CLINICAL OBSERVATION An All Natural Traditional Chinese Herbal Formula for Prostate Care
Dr. Sherman Lai CMD, Dr. Ac., B. Sc. Oriental Healing Arts Research Inc. Guelph, ON, Canada Revised Edition May 2005
Abstract: This article is designed to provide clinical observational data on Prostate Hope™ to support patients suffering from rising prostate specific antigen (PSA) levels, as well as to review the scientific literature supporting the evidence that Panax Ginseng, Ganoderma lucidum, and Scutellaria baicalensis, (while working synergistically with the sixteen other ingredients in Prostate Hope™) help to repair both the immune and digestive systems as well as cleanse and support the entire body. Sixty-eight patients participated in this clinical observation study, all previously diagnosed with elevated PSA levels. There were no controls for the patients diet and/or other forms of natural health product supplementation, in addition to Prostate Hope™. The evaluation criterion was based on the decrease, increase or no change in the PSA level. After the nine month observation period 51.5% of the observation body had a PSA decrease greater than 20%. The results of our clinical study, as well as the support from the scientific literature suggest that Prostate Hope™ could serve as an integrative therapeutic tool for prostate care. Keywords: Prostate Hope™; Prostate Cancer; PC SPES; PSA reduction; Panax Ginseng; Ganoderma lucidum; Scutellaria baicalensis
Prostate cancer is a very common
cancer, it is estimated that up to half of
form of the disease. This is largely due
to the fact that metastatic prostate cancer
radiation; translating into a problem of
is the most widespread cancer afflicting
the metastatic form prior to their initial
concern for the health care system due to
scientific literature review detailing the
findings that the nineteen ingredients in
challenge that is of an alarming concern
is the morbidity associated with prostate
importantly, the rate at which the PSA is
rising on top of an elevated PSA reading
reducing PSA levels during their time of
approaches for the treatment of prostate
treatments have been clinically proven in
fatigue, pain, swelling and hot flashes.
cancer have been linked to diet, race and
nature. All men 40 years or older should
a quarter of the world’s population, but
its philosophical and theoretical concepts
intervention of prostate cancer (this test
measures the level of PSA in the blood).
prostate that is found in elevated levels
in the blood of men with prostate cancer.
(equal to or greater than 4), the next step
result in blood stagnation, and so it is
likely it is that the tumour will spread;
cysts, abscesses, and tumours, which can
potential of spreading. The prognosis of
The six primary methods of treatment for cancer used by traditional Chinese medical practitioners are as follows: 1. Remove heat, dampness and toxicity 2. Removes stagnant blood and Qi 3. Re-balance the Qi 4. To soften and remove the mass 5. Remove the phlegm and moisture 6. Treat the cancer with poison Proposed Theory of Prostate Hope™
ingredients that work synergistically to
Patients
Hedyotis, Dyer’s Woad Leaf, Moutan,
During 2001 to 2003, sixty eight patients
Chrysanthemum, Scutellaria baicalensis,
and Anemarrhena help to cleanse heat,
Phellodendron bark, Dioscorea, Cornus,
treatment and participated in the clinical
Epidium, Lycium fruit, and Alisma help
to tonify the kidneys, while Cornus and
patient into the study was staggered as it
depended on their arrival at the Centre of
deficiencies. Licorice, Ganoderma lucidum, Poria, Panax Ginseng andSang-Qi Ginseng all help to improve the
two criteria to become eligible for entry
flow of blood and Qi. Lastly, Hedyotis, Panax Ginseng and San-Qi Ginseng also
tumour reduction. For the purpose of the
Ganoderma lucidum, Scute barbata andhedyotis, evaluating their potential in
integrative therapeutic aid for prostate
Methods and Materials Study Protocol
(equivalent to 10 capsules twice daily).
There were no controls for the patient’s
results of the patient’ PSA readings by
their medical doctor. Figure 1 represents
his research team on a monthly basis and
to Prostate Hope™ during the course of
completed every 3 months. Figure 1: Representing the percentage of patients using Prostate Hope™ that showed a decrease in their PSA level.
These results represent an efficacy rate
took part in the study showed a decrease
This clinical observation study outlines a
survival is good. According to traditional
Chinese medical theory for the treatment
toxicity, therefore cleansing the body of
clearly indicate that PSA level reduction
In a clinical TCM setting, it is not our
objective to refuse support for patients
entering the facility nor to advise them
considerations and logistical difficulty of
Therefore, we were not able to conduct a
cancer. A detailed list of the ingredients
observation study, it is also difficult for
treatments for cancer are relatively new,
further investigation is warranted. It is
also important to note however, that it is
that unfortunately there is not one direct
cancer, and that cancer therapy will have
protocol, leaving further room for error.
the patient during their battle with cancer
an effect on the results. Due to patient
and suffering felt during their fight with
to lead a better lifestyle, with less pain,
Panax Ginseng, Scutellaria baicalensis
and Ganoderma lucidum. Recent studies
nutrients, which in turn will aid in the
because of their anti-cancer properties.
Table 1 briefly outlines some of the anti-
important role in Prostate Hope™ are: Table 1: Brief description on three of the main ingredients in Prostate Hope™ that have been shown through scientific studies to promote anti-cancer effects
Article
Tumor promotion is closely related to events
such as increased activity and expression of ornithine decarboxylase (ODC) which plays an important role in cell proliferation as well as the increase in pro-inflammatory cytokines such as COX-2, which has been implicated in cancer development. Keum et al. demonstrated that Rg3, a major ginsenoside from Panax Ginseng, down regulates COX-2 and also has been studied to inhibit ODC activity. Based on the findings from this study, it is Rg3 that is responsible for Panax Ginseng anti-cancer effects.
It has been documented that Ganoderma lucidum inhibits the cell motility of highly invasive breast and prostate cancer cells. Ganoderma lucidum demonstrates this ability through the following chain of events; it inhibits the transcription of AP-1 and NFκ-231, followed by the suppression of the uPA and uPAR expression reducing the migration of the breast and prostate cancer cells. Hence, halting the process of angiogenesis.
Scutellaria baicalensis has been shown to have
a strong dose dependent anti-cancer effect both in vivo and in vitro. The inhibition of cancer growth is not due to the induction of apoptosis; the results indicate it is due to the ability to cause G0 – G1 phase arrest. It should be noted
that this herb selectively inhibits cancer cell growth and has been extensively studied to have no effect on non-cancerous cells. Therefore, the inhibition of tumor growth is not toxic to the peripheral blood lymphocytes.
The study suggests that the synergistic effect among the nineteen ingredients can be integrated into any cancer treatment protocol for prostate care with 73 percent of cases showing a reduction in PSA levels. There are also many years of documented scientific literature further supporting our findings, suggesting that the ingredients in Prostate Hope™ have an anti-cancer effect. In conclusion, we believe that Prostate Hope™ has great potential to be used as an integrative approach for prostate cancer care.
Reishi (Stem) Ganoderma lucidum
The stem of the Reishi plant is known to
affect the liver, heart, spleen and lungs.
Phellodrendron BarkCortex
This bark exerts its affect on the kidneys
Baikal Skullcap (Root) Scutellaria Anemarrhena Anemarrhena
action is to clear heat, drain fire, enrich
This herb is used to clear heat, drain fire
yin, moisten dry conditions and generate
fetus, sedate liver yang and it has also
demonstrated an inhibitory effect against
Dyer’s Woad (Leaf) Isatis Indigotica
The Dyer’s Woad Leaf affects the heart,
febrile response after a Salmonella typhi
It has been shown to clear heat, relieve
DioscoreaRadix Dioscoreae Oppositae
Dioscorea affects the kidneys, lungs and
Chrysanthemum Flos Chrysanthemi
traditional use to drain heat and relieve
CornusFructus Corni Officinalis Moutan Cotex Moutan Radicis
Cornus is known to affect the kidney and
It has a wide range of actions, including
excessive sweating, tonifies the liver and
fire, invigorating blood, dispelling blood
Rehmannia (Cooked) Radix
channels of the heart, kidney and liver.
HedyotisHerba Hedyotis Diffusae
Its main actions are to tonify and nourish
AlismaRhizoma Alismatis Orientalitis
Alisma exerts its effects on the kidneys
Rabdosia (Leaf)Rabdosia Rubescens
urination and leach out dampness as well
Poria (fushen)Sclerotium Poriae Cocos
In Chinese medicine, Poria is used for a
variety of functions. Some actions of the
the spleen, and calming the spirit.San-Qi Ginseng (Root) Panax
diuretic, a cardiotonic, an antibacterial
and anticancer agent. It is also used to
This root affects the liver, stomach and
Licorice Root Glycyrrhizae Uralensis,
and tonifies the stomach. It is known to
benefit the heart Qi and calm the spirit.
EpimediumEpimedium Grandiflorum
coughing, clears heat, relieves toxicity,
kidneys and fortify the yang. It is used
uses including anti-inflammatory effects,
use for asthmatics, gastrointestinal uses
Lycium FruitLycium barbarun Oriental GinsengPanax Ginseng
Lycium fruit affects the liver, lungs and
This herb exerts its effects the lungs and
This herb nourishes and tonifies the liver
It strongly tonifies and augments the Qi
in the lungs. It strengthens the spleen
After 6 weeks of taking Prostate Hope™
(I) 71-year-old male
After another 6 weeks of taking Prostate
also agreed to have laser surgery to trim
Hope™ at a dosage of 6 capsules 3 times
After taking Prostate Hope™ at a dosage
(III) 84-year-old male (II) 71-year-old male
PSA levels were 9, 28, 51.3 respectively
*He was prescribed Prostate Hope™ at a
* He had a bit of a digestive adjustment
*After 1 year his PSA began to rise up to
in the first week of starting the protocol
*His PSA had dropped from 53.7 to 47.6 After another 2 months of taking
(V) 64-year-old male
He will continue to take Prostate Hope™
(IV) 73-year-old male
After 1 month of taking Prostate Hope™
Hope™ at a dosage of 7 capsules 3 times
Hope™ at a dosage of 7 capsules 3 times
After another 8 weeks of taking Prostate
Hope™ at a dosage of 7 capsules 3 times
Prostate Hope™ at a dosage of 3.5grams
of June. He reported feeling really good
(VI) 63-year-old male
2003, level was at 5.4 with Gleason level
*He is very pleased with the results and
will continue to take Prostate Hope at a
Upon his next visit to the clinic, Dr. Lai
Appendix C - Ingredient List of Dr. Lai’s ABC™
Further information can be found at www.bioherbalai.com or in the clinical observational study A Chinese Herbal Formula for the Intervention and Inhibition of Cancer Metastasis (Lai, S., 2004) Hedyotis Scutellaria baicalensis Corydalis Sargassum Dioscorea Vaccaria Persica Angelica Sinensis Bupleurum Salvia Root Dipsacus Citrus Seeds Melia Atractylodes Peony (red) Hornet Nest Ganoderma lucidum Astragalus
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14. Heywood, V.H., Flowering Plants of the
5. Chen, J., Plant Foods & Nutritional
17. Keum Y., Han, S., Chun, K., Park, K.,
Nature’s Green Feast, Keats Publishing
20. Li Tiao-hua. Patterns and Treatment of
9. Fang Yao-zhong. Seven lectures on the
10. Fratkin, J.P., Chinese Herbal Patent
11. Furnell, D. Health from the Hedgerow,
23. Lu, H.C., The Chinese System of Using
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24. Ma Ruo-shui. Theoretical Foundations
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34. Sliva, D., Labarrere, C., Slivova, V.,
lucidum suppresses motility of highly
cells. Biochemical and Biophysical
27. Qin Bo-wei. Medical Lecture Notes of
Research Communications. 298:603-12
35. Tanaka, T., Tanaka’s Encyclopedia of
Medical Reference for Clinical Patterns.
36. Teeguarden, R., Chinese Tonic Herbs,
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30. Reis, S.V., Frank J. Lipp. Jr. New Plant
38. Wit, H.C.D. de. Plants of the World,
39. Zhai Ming-yi. Clinical Foundations of
40. Zhang, D., Fei, J., Xue, Li, Jiang, S., Yi,
Synthesis by Scutellaria Baicalensis.
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The GSK France Decision of March 2007 Outline of the presentation 2. Predation Test 3. Application of the test A brief history of the case • July 2000: Flavelab refers the case to CC, asks for interim measures • November 2000: CC does not grant interim measures • December 2001: Flavelab goes bankrupt • April 2002: Flavelab acquired by Panpharma – 2003