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Section 1 - product identification

MATERIAL SAFETY DATA SHEET
State of the art ingredients ∙ fast friendly service
SECTION 1 :: PRODUCT IDENTIFICATION
Chemical Name: Caffeine, anhydrous
INCI: Caffeine
SECTION 2 :: DATA ON COMPONENTS
Molecular Weight: 194.19
Chemical Characterization: C2-H10-N4-O2
FEMA number: 2224
TSV Level: 10 mg/m3
Caffeine is regulated as a nuisance particulate, not otherwise classified.
Hazardous Impurities: none
SECTION 3 :: HAZARDS IDENTIFICATION
Hazardous Material Information System (HMIS)
Health: 3 Fire: 0 Reactivity: 0 Persistence: 1
Emergency Overview: Silky white crystals or crystal ine powder with bitter taste. Efflorescent.
Toxic central nervous stimulant. Caffeine has been implicated in increased fetal losses and is
considered a possible teratogen.
Most Important Hazard: Ingestion: may cause central nervous system stimulation resulting
in insomnia, restlessness, increased respiration, delirium and may effect the cardiovascular
system.
Carcinogen status: possible teratogen
SECTION 4 :: FIRST AID MEASURES
Eyes: Flush eyes with water as a precaution. If eye irritation persists, consult with a specialist.
Skin: Wash off with soap and plenty of water. If skin irritation persists, cal a physician.
Inhalation: Move to fresh air. If symptoms persist, cal a physician.
Ingestion: If the patient is conscious, give two glasses of water and induce vomiting. Get
immediate medical attention. Never give anything by mouth to an unconscious person.
Protection of first-aiders: no hazards which require special first aid measures.
SECTION 5 :: FIRE FIGHTING MEASURES
Flash Point: not applicable
Flammable limits: 2.0-16%
Autoignition temperature: 925°C
Extinguishing media: Water spray, dry powder, foam, carbon dioxide
Fire fighting Equipment/Instructions: Do not scatter material with high pressure water
streams. Dike fire control water for later disposal. Use standard procedure for chemical fire.
Special protective equipment: Use personal protective equipment including self-contained
breathing apparatus when fighting fire in enclosed area.
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MATERIAL SAFETY DATA SHEET
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SECTION 6 :: ACCIDENTAL RELEASE MEASURES
Spill and Leak procedures
Personal Precautions
: Use personal protective equipment. Avoid dust formation.
Environmental Precautions: Dispose according to federal, state and local authorities.
Methods for cleaning up: Sweep up and shovel. After cleaning, flush away with traces of
water.
SECTION 7 :: HANDLING AND STORAGE
Technical measures/Precautions: No special technical protective measures required.
Safe handling advice: No special handling advice require
Technical measures/Storage conditions: Keep tightly closed in a dry and cool place.
Incompatible products: No special restrictions on storage with other products.
Packaging materials: Store in original container.
SECTION 8 :: EXPOSURE CONTROLS AND PERSONAL PROTECTION
Engineering measures: Provide general dilute ventilation.
Exposure limit(s): Threshold Limit Value: 10 mg/m3, Nuisance Particulate, N.O.C.
Respiratory: NIOSH approved dust respirator
Eyes: safety glasses
Skin: lightweight protective clothing, gloves
General: Handle in accordance with good industrial hygiene and safety practice
SECTION 9 :: PHYSICAL AND CHEMICAL PROPERTIES
Form: powder
Color: white
Odor: none
Boiling point: Sublimes at 178°C
Specific Gravity: 1.23
Melting point/range: 238°C
Solubility in Water: g/kg ~2.5% @ 20°C 1 gm in 46 ml water
Freezing Point: N/A
Evaporation Rate: N/A
pH value: 1% solution -6.9
% volatiles by volume: N/A
Vapor Density: N/A
Vapor Pressure: N/A
Coefficient of water/oil distribution: N/A
Decomposition temperature: unknown
Bulk density: unknown
Explosive properties: unknown
5103 Commercial Park Dr, Ste A ∙ Austin TX 7824
(512) 535::2711 ∙(512) 535::7362 fax

MATERIAL SAFETY DATA SHEET
State of the art ingredients ∙ fast friendly service
SECTION 10 :: STABILITY AND REACTIVITY
Chemical Stability: stable at normal conditions
Conditions to avoid if unstable: N/A
Incompatibility with other materials: strong acids, alkalis, oxidizers
Hazardous polymerization: does not occur
Hazardous decomposition products: N/A
Conditions to avoid: Keep containers dry and tightly closed to avoid moisture absorption and
contamination. Extreme heat may cause sublimination.
SECTION 11 :: TOXICOLOGY INFORMATION
Acute toxicity: LD50/Oral/Human 192 mg/Kg
Chronic toxicity: Chronic caffeine effects involve the status of experimental teratogen and
carcinogen. In women it has been implicated in increased fetal losses.
Human experience: Acute caffeine poisoning may cause insomnia, restlessness, tremor and
delirium, tachycardia and extrasystales.
Carcinogen content: listed as an experimental carcinogen by NTP
Additional toxicity data: R.T.E.C.S. #EV6475000, NIOSH
SECTION 12 :: ECOLOGY INFORMATION
Mobility: completely soluble.
Persistence and degradability:
Chemical oxygen demand: unknown
Biochemical oxygen demand within 5 days: (BOD5) Unknown
Bioaccumulation: unknown
Ecotoxicity effects: unknown
SECTION 13 :: DISPOSAL CONSIDERATIONS
Waste from residues/unused products: any disposal practice must be in compliance with local, state and federal laws and regulations (contact local or state environmental agency for specific rules).
SECTION 14 :: TRANSPORT INFORMATION
Not a Hazardous material for DOT shipping.
SECTION 15 :: REGULATIONS
Is general y regarded as safe (GRAS) by the USA FDACaffeine is not subjected to SARA section 313 reportingThe ingredients are listed on the TSCA inventory listCERCLA (Comprehensive Response Compensation and Liability Act): N/ASARA Title 311 (Superfund Amendments and Reauthorization Bil ): reporting not required under section 311 5103 Commercial Park Dr, Ste A ∙ Austin TX 7824
(512) 535::2711 ∙(512) 535::7362 fax

MATERIAL SAFETY DATA SHEET
State of the art ingredients ∙ fast friendly service
Foreign Inventory Status:Canadian DSL (Domestic Substance List) SECTION 16 :: COMMENTS
The information accumulated herein is believed to be accurate but is not warranted to be whether originating with Ingredients To Die For or not. Recipients are advised to confirm in advance of need that the information is current, applicable, and suitable to their circumstances.
5103 Commercial Park Dr, Ste A ∙ Austin TX 7824
(512) 535::2711 ∙(512) 535::7362 fax

Source: http://ip-173-201-38-65.ip.secureserver.net/files/MSDS_Caffeine.pdf

Pii: s0021-9150(02)00246-0

Apolipoproteins and carotid artery atherosclerosis in an elderlymultiethnic population: the Northern Manhattan stroke studyJiann-Shing Jeng a, Ralph L. Sacco a,b, Douglas E. Kargman a, Bernadette Boden-Albala a,b, Myunghee C. Paik b, Jeffrey Jones c, Lars Berglund c,a Departments of Neurology, Columbia University, New York, NY, USAb School of Public Health, Columbia University, New York,

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