GLAXOSMITHKLINE HEALTHC ARE stamping out disease GlaxoSmithKline, the pharmaceuticals company, dedicates a significant amount of resources to efforts to eliminate a crippling condition that afflicts millions of people in developing countries – building public-private partnerships along the way
When Mimoungou Haruna’s leg first started swel ing,
GlaxoSmithKline (GSK). Albendazole was original y
he was concerned. By the time it had swol en to wel
developed as a de-worming agent for animals, but it
over twice its normal size, he was justifiably horrified.
was also found to be effective against the parasites
No longer able to work, he now relies on family and
that carry LF in humans. When taken with another drug,
albendazole was shown to stop the transmission cycle
The incapacitating symptoms first appeared two
decades ago, and Haruna, now 70 years old, had no
In 1997 the World Health Assembly passed a
idea what caused them. He went to the traditional
resolution to eliminate the disease. It chose 2020 as a
healer, but the swel ing continued. The words
target date. ‘We were looking for something in keeping
‘lymphatic filariasis’(LF) had never reached his rural
with our corporate mission as a health company,’says
corner of Burkina Faso in west Africa. Only when
Minne Iwamoto, manager of GSK’s LF programme.
officials from the Ministry of Health visited his vil age to
‘Eliminating LF was an issue where we could make a
raise public awareness of the disease did he learn the
difference to mil ions of people – a tangible difference
in some of the world’s poorest communities.’
Around 120 mil ion people suffer from LF, which, as in
the case of Haruna, can lead to elephantiasis and
subsequent grotesque swel ing. Over a bil ion more are
programme of its drug. That was back in 1998. Almost
at risk of contracting the disease, which is transmitted
ten years later, the company has given away 700
by mosquitoes. Highest on the danger list are those
mil ion albendazole treatments free of charge. In 2006
living in the tropical regions of Africa and South Asia.
alone it donated 155 mil ion tablets, which calculated
The bad news is that there is no known cure for those
according to the wholesale average cost was worth
already infected. The good news, however, is that a
major programme is underway to eliminate the
The main beneficiaries of the LF programme are the
disease. This uses two prescription medicines given
drug recipients themselves. Each needs treatments
once a year, for five years, to those living in endemic
over five years, and an estimated 140 mil ion people
have been treated so far, a third of whom are children.
One of the required drugs, albendazole, is made by
For communities that complete the five-year
the international pharmaceuticals company
programme, the chances of eliminating LF are high.
■ lymphatic filariasis, a debilitating disease that affects 120 million people, mainly in Africa and the Americas, can lead to elephantiasis 10 ETHICAL PERFORMANCE BEST PRACTICE | issue 11
As wel as the health benefits, the programme also
the company
means there are fewer people, such as Haruna, who are
GlaxoSmithKline is a £23bil ion ($11.5bn) turnover
out of work because of LF. This has the knock-on
pharmaceuticals company that employs around
economic benefit of a more productive workforce for
100,000 people in more than 116 countries. Its core
activity is developing and launching new medicines and
GSK also stands to benefit. Iwamoto points out that
vaccines, and it spends nearly £400,000 an hour on
enhancing the company’s global reputation and
reaffirming its mission statement (‘Do more, feel better,
■ is pursuing 14 clinical research and development
live longer’) represent two clear outcomes from its
programmes for medicines and vaccines against
involvement. The company’s flagship LF programme
nine diseases that are particularly relevant to the
complements its other disease prevention initiatives,
which include fighting the spread of malaria and HIV.
■ donated £22 mil ion ($41m) worth of life-saving
With a social spend valued at £302mil ion last year,
antibiotics and other medicines in 2006 to support
equivalent to almost four per cent of pre-tax profits, the
company donates wel above the one per cent of pre-
■ has signed an agreement with the Russian
tax profits to which many companies aspire.
government to supply anti-retroviral medicines,
But it’s not just GSK’s external reputation that’s at
which tackle HIV/Aids, at discounted prices.
stake. ‘Employees want to work for a company thatconcerns itself with more than just profit, and thecompany’s commitment to lymphatic filariasis is good
£1m a year into the Al iance’s work on the ground. The
for employee morale,’says Iwamoto. GSK’s efforts to
money supports rol -out and management of the LF
stamp out LF, in other words, increase its standing in
programme, through activities such as technical
David Molyneux, director of the LF support centre
‘employees
and professor of tropical health science at Liverpool
University’s School of Tropical Medicine, says: ‘GSK has
work for a
shown the desire to make a large scale public-private
partnership like this real y work. It’s stuck in through
thick and thin and now the public health successes are
that concerns itself with
Although it’s a decade since the fight against LF
began, the project is stil in its early days. Each
more than
participating country must go through at least five
just profit’
years of mass drug administration – a process that only
donation programmes play in building an awareness of
around half a dozen countries have so far completed. In
GSK’s position as a leading manufacturer of medicines
the case of Haruna it’s too late, although the medical
and vaccines. Its product list covers everything from
assistance he’s received through the programme has
cancer and diabetes treatments to polio and whooping
stabilized his condition. But for mil ions of others,
there’s real hope that the end of this crippling disease
GSK is not alone in its fight against LF. From the start,
the company has always looked for other organizationswith whom to partner. Working with the World Health
■ Further information: www.filariasis.org
Organisation, GSK was instrumental in creating aworldwide coalition of health ministries, non-profitgroups and other corporate partners. Established in
2000, the Global Al iance to Eliminate LF now has more
GLAXOSMITHKLINE
than 120 member organizations, including Merck,
Many people are unaware of the disease lymphatic filariasis (LF), knowing only
another large pharmaceuticals company. In each of the
of the other mosquito-borne disease, malaria. The latter has more support, so it
countries involved, the lead is taken by the local
is reassuring that GSK has focused on LF, recognizing the devastation it causes,
ministry of health, with technical and financial
especial y as it has no known cure. Importantly, the company has not just
assistance provided by the other Al iance members.
donated drugs but helped in a practical way to build partnerships to ensure a
Participating in a public-private partnership of this
stable environment for the treatment over five years. This is almost more
size is not easy, and represents one of the ongoing
noteworthy than the donations, as it is building local capacity.
chal enges for GSK, according to Iwamoto. ‘Having acommon goal is essential for this kind of partnership to
Features that impress are:
work,’she says. ‘It’s also key that from the start
■ the holistic approach of giving aid to support management development of
everyone has a clear idea of what their particular roles
■ the project reinforces GSK’s corporate mission as a health company and
While donating albendazole is GSK’s main
boosts employee morale by showing it is about more than just profit
contribution to the Al iance, it also uses its global
■ the sheer size of GSK’s social spend at almost four per cent of pre-tax profits.
presence and contacts to get more participants andfunders on board. In addition, GSK puts approximately
PHILIPPA FOSTER BACK OBE, INSTITUTE OF BUSINESS ETHICS
issue 11 | ETHICALPERFORMANCE BESTPRACTICE 11●
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The following is a list of commonly prescribed drugs covered under the EmblemHealth pharmacy program. To obtain the complete formulary, please visit www.emblemhealth.com . The list is not all inclusive and does not guarantee coverage. We encourage you to ask your doctor to prescribe generic drugs whenever appropriate. PLEASE NOTE: Drugs listed on this document may become non-Preferred if a g