Love_molecule_the_science-behind_it

Molecule of Love
Same Compound Found in Chocolate,
Phenylethylamine Demonstrates Positive
Effects on Mood, Depression, ADHD,
Runners’ High, and Love & Monogamy
E3Live BrainON is Super Charged with the “Love Molecule”.

E3Live BrainON is a concentrated, certified organic, aqua-botanical known as AFA
(Aphanizomenon flos-aquae). E3Live BrainON is a naturally occurring food that is
innately “supercharged” with phenylethylamine (PEA), also known as "The Love
Molecule." This same compound is found in chocolate and thought to produce
chocolate’s pleasurable effects on mood. E3Live BrainON contains approximately 50
times more PEA than chocolate. Numerous studies exist demonstrating PEA's efficacy
as an anti-depressant, and its effectiveness for ADD (Attention Deficit Disorder), as
well as being involved with “runner’s high” and even the chemicals responsible for
romantic love.!

What Is the Love Molecule?
At a science-based level, PEA or phenylethylamine is an alkaloid and a monoamine.
In the human brain, it is believed to function as a neuromodulator or
neurotransmitter. A colorless liquid that forms a solid carbonate salt with carbon
dioxide (CO2) upon exposure to air, phenylethylamine in nature is synthesized from
the amino acid phenylalanine by enzymatic decarboxylation. It is also found in many
foods, especially in chocolate. It has been suggested that phenylethylamine from
chocolate and especially in E3Live Brain can have psychoactive effects. Subjects
easily notice that their mood becomes balanced and their attention and focus are
Increased. It helps people to enjoyably function at a higher level.
PEA or the Love Molecule as found In E3Live BrainON products is not an isolated
compound. It is not at all a synthetic product made in a lab. It is important to
know that the "Love Molecule" or PEA is part of the food itself and naturally occurs
in combination with numerous co-factors and micronutrients.
The Love Molecule as an Anti-Depressant
Researchers at Rush University and the Center for Creative Development in Chicago
conducted a study demonstrating PEA’s anti-depressant effects: “Phenylethylamine
(PEA), an endogenous neuroamine, increases attention and activity in animals and
has been shown to relieve depression in 60% of depressed patients. It has been
proposed that PEA deficit may be the cause of a common form of depressive illness.
Fourteen patients with major depressive episodes that responded to PEA treatment
(10-60 mg orally per day were reexamined 20 to 50 weeks later. The antidepressant
response had been maintained in 12 patients. Effective dosage did not change with
time. There were no apparent side effects. PEA produces sustained relief of
depression in a significant number of patients, including some unresponsive to the
standard treatments. 1
1) Sabelli H; Fink P; Fawcett J; Tom C. Sustained antidepressant effect of PEA
replacement. J Neuropsychiatry Clin Neurosci, 1996 Spr, 8:2, 168-71.
In the book Natural Remedies for Depression by Donald Brown, N.D., Alan R. Gaby,
M.D., and Ronald Reichert, N.D., the L form of phenylalanine is discussed:
“L-Phenylalanine, the naturally occurring form of phenylalanine, is converted in the
body to L-tyrosine. D-phenylalanine, which does not normally occur in the body or
in food, is metabolized to phenylethylamine (PEA), a compound that occurs
normally in the human brain and has been shown to have mood-elevating effects.
Decreased urinary levels of PEA (suggesting a deficiency) have been found in some
depressed patients.7 Although PEA can be synthesized from L-phenylalanine, a
large proportion of this amino acid is preferentially converted to L-tyrosine. D-
phenylalanine is therefore the preferred substrate for increasing the synthesis of
PEA—although L-phenylalanine would also have a mild antidepressant effect
because of its conversion to L-tyrosine and its partial conversion to PEA. Because
D-phenylalanine is not widely available, the mixture D,L-phenylalanine is often used
when an antidepressant effect is desired."
Interestingly, anecdotal reports indicate that PEA also appears to work for grief, a
somewhat different form of depression. However, no studies have been formally
conducted.
The Chemicals of Love
Phenylethylamine has been identified as one of the chemicals involved with love and
monogamy. In a 2002 CNN report, Happily ever after? It’s all in your head, Elina
Fuhrmann reports that some scientists and psychologists say that love may be
dependant on a cocktail of brain chemicals which may be associated with the success
or failure of love relationships. These chemicals, dopamine, norepinephrine and
phenylethylamine act on the limbic system, which is the emotional center of the
brain and may be responsible for the feelings of euphoria and ecstasy experienced
during new love. Scientists propose that these chemicals wear off after a few months
to a few years and may explain why people fall out of love, or take couples to the
place where real love begins. Neurobiologists at Emory University in Atlanta, Georgia
conducted an animal study injecting voles with oxytosin (the brain chemical involved
with bonding and long-term attachment) and vasopressin, deemed “the monogamy
gene.” By injecting the voles with these two chemicals, the scientists were able to
cause the voles to bond and mate for life. But the question remains, which comes
first, the love or the chemicals? Is there a love and monogamy pill in our future? If
so, it very well may include significant amounts of PEA.
1) Link: http://archives.cnn.com/2002/HEALTH/02/14/love.chemistry/index.html
Same Compound in Chocolate
Phenylethylamine is the same compound found in chocolate, that is believed to
produce chocolate’s positive effects on mood. The phenylethylamine in chocolate is
believed to work by making the brain release b-endorphin, an opioid peptide which
is the driving force behind its pleasurable effects.1
“Runner’s High” Explained:
Exercise Found to Raise PEA Levels

From the book review Is ‘Runners’ High’ a Cure for Depression? by Daniel DeNoon,
reviewed By Charlotte Grayson. (www.webmd.com - Sept. 27, 2001).
“.phenylethylamine, or PEA, is a natural stimulant produced by the body. A
British research team reports early findings suggesting that moderate exercise
increases PEA levels for most people. They argue that this increase causes the
euphoric mood often called “runners’ high.” And because depressed people tend to
have low PEA levels, the researchers say there now is an explanation of why exercise
has a natural antidepressant action.
“We are not advocating PEA as a drug,” study author E. Ellen Billett, Ph.D., tells
WebMD. “What we are trying to say is now there is more chemical evidence for why
runners’ high occurs. We hope this information might give doctors more confidence
in prescribing exercise for mild depression and as an adjunct to drug therapy.”
The Nottingham Trent University research team studied 20 healthy young men. The
men had their PEA levels measured after one day of no exercise and after one day of
moderate exercise (30 minutes on a treadmill at 70% of their maximum heart rate).
All but two of the men had increased PEA levels 24 hours after their exercise. The
amount of PEA increase varied from person to person. Interestingly, only three of the
men rated the exercise as “hard,” and two of these men had the greatest increase in
PEA.

Hector Sabelli, MD, PhD, studied PEA while a professor at Chicago’s Rush University.
Now director of the Chicago Center for Creative Development, Sabelli says that the
new findings fit exactly with all of his own experiments.
“What we have seen is that PEA metabolism is reduced in people who are
depressed,” Sabelli tells WebMD. “If you give PEA to people with depression, about
60% show an immediate recovery -- very fast, a matter of half an hour.”
So what about the natural substances called endorphins, which have previously been
linked to runners’ high? Billett says that endorphins don’t penetrate the brain as
easily as PEA does -- so she thinks PEA may be the true basis for the good mood one
gets from a workout. Sabelli is not so quick to rule out endorphins, however, and
says that the natural compounds probably interact in various ways.
“We think PEA is part of the reward of exercise,” Billett says, adding that it might be
affecting other brain chemicals and that it’s likely there are normal differences
between individuals. “Some will respond to exercise, some won’t.”
The "Love Molecule" (PEA) is Safe.
Research Abstract from the Centre for Molecular Design in Beerse, Belgium:
“.Despite its short half-life, phenylethylamine attracts attention since it can
potentiate catecholaminergic neurotransmission and induce striatal hyperreactivity.
Subnormal phenylethylamine levels have been linked to disorders such as
attention deficit and depression; the use of selegiline (Deprenyl) in Parkinson’s
disease may conceivably favor recovery from deficient dopaminergic
neurotransmission by a monoamine oxidase-B inhibitory action that
increases central phenylethylamine. . The importance of phenylethylamine in
mental disorders is far from fully elucidated but the evolution of phenylethylamine
concentrations in relation to symptoms remains a worthwhile investigation for
individual psychotic patients.
PEA Replacement
In a 1996 study, the effects of phenylethylamine (PEA) replacement were studied. It
was found that PEA, an endogenous neuroamine, increased attention and activity in
animals and has been shown to relieve depression in 60% of depressed patients. It
has been proposed that PEA deficit may be the cause of a common form of
depressive illness. Fourteen patients with major depressive episodes that responded
to PEA treatment (10-60 mg orally per day, with 10 mg/day selegiline to prevent
rapid PEA destruction) were reexamined 20 to 50 weeks later. The antidepressant
response had been maintained in 12 patients. Effective dosage did not change with
time. There were no apparent side effects. PEA produces sustained relief of
depression in a significant number of patients, including some unresponsive to the
standard treatments. PEA improves mood rapidly but does not produce tolerance.

ADHD & PEA
Human Studies
In a number of controlled studies, by measuring urinary excretion levels, PEA was
found to be significantly lower in children with ADHD and LD (learning disability). A
decreased level of PEA is considered to potentially play an important role for the
pathogenesis of LD and ADHD.2 Beta-phenylethylamine (b-PEA), a biogenic trace
amine, acts as a neuromodulator in the nigrostriatal dopaminergic pathway and
stimulates the release of dopamine.3

Animal Studies
In a number of animal studies, neurotransmitters were shown to be depressed. Trace
amines (TAs) are present in the central nervous system in which they up-regulate
catecholamine release and are implicated in the pathogenesis of addiction, attention-
deficit/hyper-activity disorder, Parkinson’s disease, and schizophrenia.

Enjoyably Function at a Higher Level
At a less technical and more practical level, PEA or the Love Molecule as innately
occurring in E3Live BrainON, uniquely promotes and enhances focus and attention
and evenly balances mood as a one hundred percent food-based anti-depressant.
Gabriel Cousens, MD, Founder of the Tree of Life Rejuvenation Center, recommends
E3Live BrainON to patients suffering from depression over and above
pharmaceuticals for the preceding reasons plus for the smooth energy boost
experienced by subjects.
Dr. Cousens states: “E3Live BrainON is specific for our nervous system, brain
function and the quality of our consciousness. PEA (“the Love Molecule”) is specific
food for drug addiction, alcoholism, increased hyperactivity, increased attention
deficit disorders, and depression. More than any other food, it enables us to make a
paradigm shift and enjoy a sense of well-being. There's a quality of joy that's really
subtle that many people experience with E3Live BrainON”
I've had people who've been depressed for years and years, and literally, within a
few days after receiving E3Live BrainON, their depression lifts. This is because AFA
gets to the root of helping heal the addictive brain chemistry, which is behind a lot of
depression. I discuss this at length in my new book, Depression Free For Life. People do not have a Prozac® deficiency. That approach doesn't get to the root of the problem. My depression healing rate using natural foods, including AFA, nutritional supplements and basic lifestyle changes, without the necessity of using any pharmaceutical drugs, Prozac® or anything like that, is over 90%. No drug can compete with that, period.” E3Live BrainON is the most nutrient-dense food known to humankind. In this sense, it is peerless product. It is a wild-grown, raw, organic and naturally occurring food, not a synthetic product. Dr. Brian Clement, Director of the Hippocrates Institute, simply states that this is “the most nutritious food on the planet.” The “Love Molecule”, as found in E3Live BrainON, is documented in scientific research and well-founded in biochemical and medical literature.

Source: https://www.e3live.com/pdfs/Love_Molecule_the_Science_Behind_It.pdf