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Cvxi2013_eng_extended_ii

Roberto Sassi
phone: (+39)3204378915, e-mail: roberto.sassi@unimi.it PROFESSIONAL EXPERIENCE
Università degli Studi di Milano
Dipartimento di Infomatica [Computer Science Department] Ricercatore Confermato (Assistant Professor, Italian SSD: INF/01) Taught graduate and undergraduate classes on: digital signal processing, digital image processing, intelligent systems, programming (C / Java / PHP). Research interests included: • Signal Processing of biological signals, with particular regard to ECG (atrial fibrillation, T- Wave alternans and repolarization heterogeneity) and, more recently, neuronal recordings (deep brain stimulation). • Time series analysis, with focus on non-linear methods and long range dependences in • Biometrics and techniques which might help ensuring privacy when adopting identification procedures employing biometrics • Applied Mathematics, focusing on long term extrusion of non-Newtonian fluids and synchronization of coupled non-linear oscillators Sensure s.r.l.
Scientific advisor (part time) and co-owner Sensure s.r.l. is a successful hi-tech industrial spin-off of the University of Milan, active in the field of quality control through machine vision and state-of-the-art neural classifiers. Dr. Sassi, with endorsement of the University, acted as part-time scientific advisor in the starting phase, up to the point in which the company started being profitable. Politecnico di Milano
Dipartimento di Bioingegneria [Biomedical Engineering] Postdoctoral Researcher Supervisor: Prof. S. Cerutti Conducted research on ECG signals of patients undergoing atrial fibrillation in collaboration with prof. Pierre Maison-Blanche (Lariboisiere University Hospital, Paris, France) and Ela Medical (Paris, France). Imperial College
Department of Mathematics Visitor (Applied Mathematics division) Supervisor: Prof. Richard V. Craster Conducted research on spectral algorithms for reaction-diffusion equations. University of California at Santa Cruz
Baskin School of Engineer, Department of Applied Mathematics and Statistics Postdoctoral Researcher Supervisor: Prof. Neil J. Balmforth Conducted research on non-Newtonian fluids (common in biology), in particular when one dimension of the fluid is in first approximation negligible with respect to the others (lubrication approximation). Hewlett-Packard Italiana s.p.a.
Stage within the Medical Division Supervisors: Piero Brambilla e Alberto Oggioni Integration of a clinical data management system with intensive care instrumentations; developed a C prototypal version of a synchronous network driver and client. EDUCATION
Politecnico di Milano
Dipartimento di Bioingegneria [Biomedical Engineering] Dottorato di Ricerca in Bioingegneria (Ph.D. in Biomedical Engineering) Ph.D. dissertation (defended on March 5, 2001): “Analysis of heart rate variability complexity through fractal and multivariate approaches”. Supervisor: Prof. Sergio Cerutti University of California at Santa Cruz, (CA, USA) & ISAC-CNR, Torino (Italy) Supervisors: Prof. Neil J. Balmforth and Dr. Antonello Provenzale Conducted research on hierarchically coupled maps. A large number of logistic maps were coupled together as a mathematical metaphor for complex natural systems with hierarchical organization. (3/2000–6/2000, 11/2000) ISAC-CNR, Torino & Politecnico di Milano, (Italy)
Supervisors: Dr. Antonello Provenzale and prof. Maria Gabriella Signorini Conducted research on the possible multifractal structure of heart rate variability with application to 24-hours inter-beats series. (10/1999–4/2000) Università degli Studi di Pavia (Italy) & Politecnico di Milano (Italy) Supervisors: prof. Maria Gabriella Signorini and prof. Giovanni Magenes Conducted research on fetal monitoring. (3/1999–6/2000) Woods Hole Oceanographic Institution (MA) & University of California at Santa Cruz (CA), USA Supervisor: Prof. Neil J. Balmforth As GFD fellow, conducted research on phase-coupled nonlinear oscillators (continuous and discrete Kuramoto models). The transition to synchronization in the continuum model was analyzed. Numerical methods and perturbation theory were used to study the patterns of synchronization that form beyond transition. (6/1999–8/1999, 12/1999) Columbia University, New York (NY), USA Supervisor: Prof. Edward A. Spiegel Conducted research on chaotic nonlinear dynamical system displaying riddled basins of attraction. (10/1998–12/1998). Politecnico di Milano
Laurea (equivalent to a Master & Bachelor degrees) in Electronic Engineering (summa cum laude) Master's Thesis (defended on December 20, 1996, in Italian): “Studio dell’entropia approssimata per la classificazione di serie temporali: applicazioni al segnale di variabilità cardiaca” (Heart Rate Variability signals classification through Approximate Entropy). Supervisors: Prof. Sergio Cerutti and prof. Maria Gabriella Signorini Liceo Scientifico “Martiri di Belfiore”
Maturità scientifica (high school degree, 58/60). FELLOWSHIPS
• 2003, «SNIA S.p.A. - dott. Ennio Denti» postdoctoral fellowship, Politecnico di Milano, Italy. • 1999; «GFD Fellow», Geophysical Fluid Dynamics Program, Woods Hole Oceanographic Institution, MA, USA. • 1998, «Isabella Sassi Bonadonna» fellowship, Associazione Elettrotecnica ed Elettronica Italiana (AEI), Italy. LANGUAGE SKILLS
Mother-tongue: Italian. Fluent in: English. ADDITIONAL INFORMATION
IEEE senior member since 2012 (member since 2006). AEIT member (IEEE Italian sister society) since 1998. ESC (European Society of Cardiology) active member of the e-Cardiology working group. ISCE (International Society for Computerized Electrocardiology) member Licenced in Italy to the profession of engineer since 1998. Date and place of birth: October 16, 1971 in Mantova (Italy). Nationality: Italian. OTHER ACTIVITIES
He acted as reviewer for the following international journals:
• IEEE Transactions on Biomedical Engineering • Annals of Biomedical Engineering • Medical Engineering and Physics • Biomedical Signal Processing and Control • Computer Methods and Programs in Biomedicine • Computers in Biology and Medicine • Medical & Biological Engineering & Computing • Journal of Electrocardiology • Physiological Measurement • European Journal of Applied Physiology • Engineering in Medicine and Biology Magazine • Frontiers in Computational Physiology and Medicine • IEEE Transactions on Information Forensics & Security • IEEE Transactions on Instrumentation & Measurement • Chaos: An Interdisciplinary Journal of Nonlinear Science • Chaos, Solitons & Fractals Journal of Non-Newtonian Fluid Mechanics • Physica A: Statistical Mechanics and its Applications • Journal on Computational Intelligence in Bioinformatics and Systems Biology • IEEE Systems Journal • Signal Image and Video Processing • Journal of Engineering Mathematics He was a member of the Programme Committee of / acted as a reviewer for the following international
conferences:
• Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC (in the years: • Mediterranean Conference on Medical and Biological Engineering and Computing, MEDICON (in the years: • IEEE Symposium Series on Computational Intelligence 2013 (SSCI 2013) • Bio- and Medical Informatics and Cybernetics, BMIC (in the years: 2010 and 2011) • IEEE Workshop on Biometric Measurements and Systems for Security and Medical Applications, BioMS (in • International Joint Conference on Neural Networks, IJCNN (in the years: 2010, 2011, 2012 and 2013) • IEEE International Conference on Computational Intelligence and Virtual Environments for Measurements Systems and Applications, CIVEMSA (in the year 2013). • IEEE International Conference on Computational Intelligence for Measurement Systems and Applications, • IEEE International Conference on Virtual Environments, Human-Computer Interfaces, and Measurement Systems, VECIMS (in the years: 2011, 2012) • International Conference on Knowledge-Based and Intelligent Information & Engineering Systems, KES (in the • IEEE International Conference on Information Technology and Applications, ITAB (in the year 2010) In 2011 he participated as a Panel Member (Biomedical Engineering subarea) in the evaluation process to select the
funded research projects for the Health Sciences 2010 call of the Portuguese Foundation for Science and Technology
(FCT).
He is a panel member of the commission which assess the applications and grants the AEIT (Associazione
Elettrotecnica ed Elettronica Italiana) «Isabella Sassi Bonadonna» research fellowship ($16.000 - $25.000).
He is a panel member of the commission which assess the applications and grants the «Francesco Rodella» research
fellowship (Associazione Rodella onlus, Montichiari, BS, €10.000).
RESEARCH
The research activity has been mainly focused in the fields of biomedical signal processing and applied mathematics. The methodological techniques have been exploited also to address related challenges in image processing and computer science, mainly biometrics. Biomedical time series analysis
Nonlinear methods for Heart Rate Variability
The study of biological time series with metrics developed within the framework of nonlinear dynamical systems had been a constant focus. The main field of application was the study of long-term fluctuations of Heart Rate Variability (HRV). The main problems tackled were: • Theoretical aspects related to: multifractality of HRV, reliability of nonlinear metrics, missing data, long-tails of the inter-beats increments probability density function. • Self-similarity, regularity and entropy measures (also multi-scales). Past and active main collaborations: prof Sergio Cerutti and prof. Maria Gabriella Signorini (Politecnico di Milano), Dr. Antonello Provenzale (ISAC-CNR), prof. Edward A. Spiegel (Columbia University, New York), prof. Marek Malik (St. George's, University of London, UK) and prof. George Manis (University of Ioannina, Greece). Biomedical signal analysis
ECG of patients undergoing atrial fibrillation
The research focused on robust and efficient algorithms for the automatic analysis of electrocardiographic (ECG) signal recorded from patients undergoing episodes of atrial fibrillation. Main problems tackled: - Separation of the Atrial and ventricular activity (both in ECG and endocavitary recordings) - Mechanisms of maintenance and termination of atrial fibrillation and the effect of drugs on atrial organization. Past and active main collaborations: prof. Luca T. Mainardi and prof. Sergio Cerutti (Politecnico di Milano), prof. Pierre Maison-Blanche (Lariboisiere University Hospital, Paris). Fetal Heart Rate (FHR) and tocodynamometer (TOCO) signals
The research focused on the analysis of fetal heart rate (FHR) variability and tocodynamometer (TOCO) signals collected during gestation. Past and active main collaborations: prof. Giovanni Magenes (University of Pavia) and prof. Maria Gabriella Signorini (Politecnico di Milano), prof. Enrico Ferrazzi, Dott.ssa Tamara Stampalija (Università di Milano). Myocardial repolarization heterogeneity
Temporal heterogeneity of ventricular repolarization is a key quantity for the development of ventricular reentrant arrhythmia. The research focuses on: • developing a novel ECG based estimator of the standard deviation of ventricular myocytes’ repolarization times based on a electrophysiological model. • developing new indexes for quantification of T-Wave Alternans (TWA). Past and active main collaborations: prof. Luca T. Mainardi (Politecnico di Milano), prof. Pablo Laguna, prof. José F. Rodriguez, prof. Esther Pueyo (University of Zaragoza, Spain), prof. Laura Burattini (Università Politecnica delle Marche, Italy). Applied Mathematics
Synchronization of coupled non-linear oscillators
Motivation: understanding more precisely synchronization mechanisms in biological phenomena, at the basis of signals like ECG or EEG, thought the study of simplified models. The scenarios of analysis had been: • mean-field phase-coupled oscillators, a situation resembling that of the sinoatrial-node cells, which start the • hierarchically coupled logistic maps, a mathematical metaphor of complex natural and biological systems, as Past and active main collaborations: prof. Neil Balmforth (University of British Columbia, Canada), Dr. Antonello Provenzale (ISAC-CNR). Non-Newtonian fluid dynamics
The theoretical researched focused on non-Newtonian fluids (common in biology), in particular when one dimension of the fluid is in first approximation negligible with respect to the others (lubrication approximation). Numerical algorithms to integrate the resulting system of partial differential equations were developed and analytical approximation derived (for short and long time scales). The work was mainly carried out at the University of California at Santa Cruz (CA, USA), under the supervision of prof. Neil Balmforth and at Imperial College (UK) with the collaboration of prof. Richard V. Craster. Privacy protection in biometrics identification procedures
Aspects related to safety of biometrics and biometric encryption (privacy) were addressed. In particular, an original algorithm that allows the verification of the identity of an individual based on a combination of multiple biometric features was developed and patented. Subsequently, the problem of “continuous” multimodal biometric authentication was tackled for those applications where operator-substitution must be avoided after an initial identification. Past and active main collaborations: prof. Vincenzo Piuri, Dr. Fabio Scotti and Dr. Stelvio Cimato, (Università di Milano). Other fields of study
Research has ranged in other areas than those listed above. In general the original contribution was always derived from a common methodological background. For example: • statistical estimates of the modelling errors in an original technique designed to evaluate the volume of worn material in acetabular component from failed hip prosthesis implants; • study of spectral methods for the solution of 2D partial differential equations of diffusion-reaction type (that arise from disparate biological or physical phenomena). BIBLIOGRAPHY
A. Published papers
[A24] V. D. A. Corino, M. W. Rivolta, R. Sassi, F. Lombardi and L. T. Mainardi, Ventricular activity cancellation in
electrograms during atrial fibrillation with constraints on residuals' power, Medical Engineering and Physics, 2013.
ISSN: 1350-4533. [Published online, DOI: 10.1016/j.medengphy.2013.07.010].
[A23] L. T. Mainardi and R. Sassi, “Some theoretical results on the observability of repolarization heterogeneity on
surface ECG”, Journal of Electrocardiology, vol. 46(3), pp. 270-275, 2013. ISSN: 0022-0736.
[A22] R. Sassi and L.T. Mainardi, “Theoretical comments on reproducibility and normalization of TWA measures.
Journal of Electrocardiology, vol. 46(2), pp. 132-135, 2013. ISSN: 0022-0736.
[A21] M. Bezzi, S. De Capitani di Vimercati, S. Foresti, G. Livraga, P. Samarati, and R. Sassi, “Modeling and preventing
inferences from sensitive value distributions in data release”, Journal of Computer Security, vol. 20(4), pp. 393-436,
2012. ISSN: 0926-227X.
[A20] R. Sassi, and L. T. Mainardi, “T-wave alternans: lessons learned from a biophysical ECG model”, Journal of
Electrocardiology, vol. 45(6), pp. 566-570, 2012. ISSN: 0022-0736.
[A19] R. Sassi, and L. T. Mainardi, “An estimate of the dispersion of repolarization times based on a biophysical
model of the ECG”, IEEE Transactions on Biomedical Engineering, vol. 58(12), pp. 3396-3405, 2011. ISSN: 0018-9294.
[A18] L. T. Mainardi and R. Sassi, “Analysis of T-wave alternans using the dominant T-wave paradigm”, Journal of
Electrocardiology, vol. 44, pp. 119-125, 2011. ISSN: 0022-0736.
[A17] R. Sassi, V. D. Corino and L. T. Mainardi, “Analysis of Surface Atrial Signals: Time Series with Missing Data?”,
Annals of Biomedical Engineering, 37, 2082-2092, 2009. ISSN: 0090-6964. IF JCR 2009: 2.409
[A16] R. Sassi, M. G. Signorini and S. Cerutti, “Multifractality and heart rate variability”, Chaos, vol. 19, pp. 028507-1-
5, 2009. ISSN: 1054-1500. IF JCR 2009: 1.795
[A15] A. Azzini, S. Marrara, R. Sassi, and F. Scotti, “A fuzzy approach to multimodal biometric continuous
authentication, Fuzzy Optimization and Decision Making”, vol. 7, pp. 243-256, 2008. ISSN: 1568-4539. IF JCR 2008:
N.A.
[A14] S. Cimato, R. Sassi, and F. Scotti, “Biometrics and privacy”, Recent Patents on Computer Science, vol. 1, pp.
98-109, June 2008. ISSN: 1874-4796. IF JCR 2008: N.A.
[A13] S. Cerutti, F. Esposti, M. Ferrario, R. Sassi, M. G. Signorini. “Long-term invariant parameters obtained from 24-
h Holter recordings: a comparison between different analysis techniques”. Chaos 17, 015108-1-9 (2007). ISSN: 1054-
1500. IF JCR 2007: 2.188
[A12] Roberto Maestri, Gian Domenico Pinna, Alberto Porta, Rita Balocchi, Roberto Sassi, Maria Gabriella Signorini,
Maria Dudziak, Grzegorz Raczak. “Assessing nonlinear properties of heart rate variability from short-term recordings:
are these measurements reliable?”. Physiological Measurement 28, 1067-1077 (2007). ISSN: 0967-3334. IF JCR 2007:
1.412
[A11] N. J. Balmforth, R. V. Craster, P. Perona, A. C. Rust, R. Sassi. “Viscoplastic dam breaks and the Bostwick
consistometer “. Journal of Non-Newtonian Fluid Mechanics, 142, 63-78 (2007). ISSN: 0377-0257. IF JCR 2007: 1.704
[A10] R. Maestri, G.D. Pinna, A. Accardo, P. Allegrini, R. Balocchi, G D'addio, M. Ferrario, D. Menicucci, A. Porta, R.
Sassi
, M.G. Signorini, M.T. La Rovere, S. Cerutti. “Nonlinear indices of Heart Rate Variability in chronic heart failure
patients: Redundancy and comparative clinical value”. Journal of Cardiovascular Electrophysiology, 18, 425-433 (2007).
ISSN: 1045-3873. IF JCR 2007: 3.475
[A9] Valentina D.A. Corino, Roberto Sassi, Luca T. Mainardi, Sergio Cerutti. “Signal processing methods for
information enhancement in atrial fibrillation: spectral analysis and non-linear parameters”. Biomedical signal
processing and control, 1, 271-281 (2006). ISSN: 1746-8094. IF JCR 2006: N.A.
[A8] N. J. Balmforth, R. V. Craster, A. Rust, R. Sassi, “Viscoplastic flow over an inclined surface”. Journal of Non-
Newtonian Fluid Mechanics, 139, 103-127 (2006). The paper was further republished with several typographical
errors removed in J. Non-Newtonian Fluid Mech. 142, 219–243 (2007). ISSN: 0377-0257. IF JCR 2006: 1.449
[A7] R. Maestri, G. D. Pinna, R. Balocchi, G. d'Addio, M. Ferrario, A. Porta, R. Sassi, M. G. Signorini, M. T. La Rovere,
“Clinical correlates of non-linear indices of heart rate variability in chronic heart failure patients”. Biomedizinische
Technik, 51, 220-223, (2006). ISSN: 0013-5585. IF JCR 2006: 0.835
[A6] R. Sassi, S. Cerutti, K. Hnatkova, M. Malik and M. G. Signorini, “HRV scaling exponent identifies post-infarction
patients who might benefit from prophylactic treatment with Amiodarone”, IEEE Transactions on Biomedical
Engineering, 53, 103-110 (2006). ISSN: 0018-9294. IF JCR 2006: 2.302
[A5] N. J. Balmforth, R. V. Craster and R. Sassi, “Dynamics of cooling viscoplastic domes”, Journal of Fluid Mechanics,
499, 149-182 (2004). ISSN: 0022-1120. IF JCR 2004: 1.853
[A4] Neil J. Balmforth, Antonello Provenzale and Roberto Sassi, “A hierarchy of coupled maps”, Chaos, 12, 719-731
(2002). ISSN: 1054-1500. IF JCR 2002: 1.982
[A3] N. J. Balmforth, R. V. Craster and R. Sassi, “Shallow viscoplastic flow on an inclined plane”, Journal of Fluid
Mechanics, 470, 1-29 (2002). ISSN: 0022-1120. IF JCR 2002: 1.882
[A2] M. T. Raimondi, R. Sassi and R. Pietrabissa, “A method for the evaluation of the change in volume of retrieved
acetabular cups”, Proceedings of the Institution of Mechanical Engineering, Part H (The Journal of Engineering in
Medicine), 214, 577-587 (2000). ISSN: 0954-4119. IF JCR 2000: 0.892
[A1] Neil J. Balmforth, Roberto Sassi, “A shocking display of synchrony”, Physica D, 143, 21-55 (2000). ISSN: 0167-
2789. IF JCR 2000: 1.643
B. Book’s chapters
[B3] F. Scotti, S. Cimato and R. Sassi, “Biometric privacy” in Encyclopedia of Cryptography and Security, 2nd ed., pp. 101-
104, H.C.A. van Tilborg and S. Jajodia editors. (Springer, 2011). ISBN: 978-1-441-95905-8.
[B2] S. Cimato, M. Gamassi, V. Piuri, R. Sassi, F. Scotti. “Privacy in Biometrics” in: Biometrics: Theory, Methods, and
Applications
, pp. 633-654, N. V. Boulgouris, K. N. Plataniotis and E. Micheli-Tzanakou editors. (IEEE/Wiley Press, 2009).
ISBN: 978-0-470-24782-2.
[B1] Maria G. Signorini, Roberto Sassi, Sergio Cerutti, “Assessment of nonlinear dynamics in heart rate variability
signals” in Nonlinear biomedical signal processing, Volume II: Dynamic Analysis and Modelling, Metin Akay eds, pp 263-281
(IEEE Press, New York, 2000). ISBN: 978-0-7803-6012-9.
C. Conference proceedings
[38] R. Donida Labati, R. Sassi, F. Scotti, “ECG Biometric Recognition: Permanence Analysis of QRS Signals for 24
Hours Continuous Authentication”, in Proc. of the IEEE International Workshop on Information Forensics and
Security (WIFS 2013), Guangzhou, China, November 18-21, 2013. [Accepted].
[37] M.W. Rivolta, L.T. Mainardi, R. Sassi and V.D.A. Corino, “Synthetic Atrial Electrogram Generator”, in XIII
Mediterranean Conference on Medical and Biological Engineering and Computing 2013 (MEDICON 2013), IFMBE
Proceedings vol. 41, pp. 670-673, Seville (Spain), 25-28 September 2013. ISSN: 1680-0737. ISBN: 978-3-319-00845-5,
Springer International Publishing.
[36] J. F. Rodriguez, R. Sassi, E. Pueyo, L. Mainardi, “Repolarization Variability Mechanisms and its Relation with
Cardiac Arrhytmogenesis”, in Computing in Cardiology, Zaragoza (Spain) September 22-25, 2013, vol. 40, 4 pp. [In
press].
[35] R. Sassi, L. T. Mainardi, P. Laguna, J. F. Rodriguez, “Validation of the V-index through Finite Element 2D
Simulations”, in Computing in Cardiology, Zaragoza (Spain) September 22-25, 2013, vol. 40, 4 pp. [In press].
[34] L. Mainardi, D. Di Donato, D. Falcone and R. Sassi, “Improved Estimation of V-Index Based on Analytic Forms of
Dominant T-Wave”, in Computing in Cardiology, Zaragoza (Spain) September 22-25, 2013, vol. 40, 4 pp. [In press].
[33] M. Aktaruzzaman and R. Sassi, “Sample Entropy Parametric Estimation for Heart Rate Variability Analysis”, in
Computing in Cardiology, Zaragoza (Spain) September 22-25, 2013, vol. 40, 4 pp. [In press].
[32] A. Bonissi, R. Donida Labati, L. Perico, R. Sassi, F. Scotti, L. Sparagino, “A Preliminary Study on Continuous
Authentication Methods for Photoplethysmographic Biometrics”, in Proc. of the 2013 IEEE Workshop on Biometric
Measurements and Systems for Security and Medical Applications (BioMS 2013), Napoli, Italy, pp. 28-33, September 9,
2013. ISBN: 978-1-4799-0626-0. [In press].
[31] M. W. Rivolta, F. Badilini, L. T. Mainardi, M. Vaglio, R. Sassi, “Quantification of ventricular repolarization
heterogeneity during sotalol administration using the V-index”, in 38th Annual ISCE (International Society for
Computerized Electrocardiology) Conference, San Jose (CA, USA) April 17-21, 2013.
[C30] R. Sassi, and L. T. Mainardi, “Quantification of Spatial Repolarization Heterogeneity: Testing the Robustness of
a New Technique”, in Computing in Cardiology, Krakòw (Poland) September 9-12, 2012, vol. 39, pp. 69-72. ISSN:
0276-6574.
[C29] M. W. Rivolta, L. T. Mainardi, and, R. Sassi, “A novel measure of Atrial Fibrillation Organization based on
Symbolic Analysis”, in Computing in Cardiology, Krakòw (Poland) September 9-12, 2012, vol. 39, pp. 813-816. ISSN:
0276-6574.
[C28] R. Sassi, M. W. Rivolta, L. T. Mainardi, A. L. P. Ribeiro, and F. Lombardi, “Spatial repolarization heterogeneity
and survival in Chagas disease”, in 7th International Workshop on Biosignal Interpretation, BSI2012, Como (Italy) July
2-4, 2012. (Published online).
[C27] R. Sassi, and L. T. Mainardi, “T-wave alternans: lessons learned from a biophysical ECG model”, in 37th Annual
ISCE (International Society for Computerized Electrocardiology) Conference, Birmingham (AL, USA) April 20-24,
2012. The abstract was published in the Journal of Electrocardiology 45(6), 695-696, 2012.
[C26] L. T. Mainardi, M. Rivolta, R. Scanziani, V. Corino, R. Sassi, “Cancellation of Ventricular Activity in Endocavitary
Recordings during Atrial Fibrillation by Particle Swarm Optimization”, in Computing in Cardiology, Hangzhou (China)
September 18-21, 2011, vol. 38, (In press). ISSN: 0276-6574.
[C25] R. Sassi; L.T. Mainardi; S. Cerutti, “Amplitude of Dominant T-Wave Alternans assessment on ECGs obtained
from a biophysical model,” Engineering in Medicine and Biology Society,EMBC, 2011 Annual International Conference
of the IEEE, pp.5872-5875, 2011. ISBN: 978-1-4244-4121-1.
[C24] R. Sassi and L. T. Mainardi, “Refined Estimate of the Dominant T-Wave”, in Computers in Cardiology, Belfast
(UK) September 26-29, 2010, vol. 37, pp. 845-848. ISSN: 0276-6574. ISBN: 978-1-4244-7318-2.
[C23] L. T. Mainardi and R. Sassi, “Analysis of T Wave Alternans Using the Dominant T-wave”, in International
Congress on Electrocardiology (ICE), Lund (Sweden) June 3–5, 2010. The short paper was published in the Journal of
Electrocardiology 44 (2), e6-e6, 2011. ISSN: 0022-0736.
[C22] R. Sassi, “Characterizing Histograms of Heartbeat Interval Differences with Gaussian Mixture Densities”, in
Computers in Cardiology 2009, Park City (Utah, USA), vol. 36, pp. 157-160. ISSN: 0276-6574. ISBN: 978-1-4244-
7281-9.
[C21] S. Cimato, M. Gamassi, V. Piuri, R. Sassi, and F. Scotti, A Multi-biometric Verification System for the Privacy
Protection of Iris Templates, in Proceedings of the International Workshop on Computational Intelligence in Security
for Information Systems CISIS’08 , Genova, Italy, 23-24 October 2008. Advances in Soft Computing, vol. 53, pp. 227-
234, 2009 (Springer Berlin, Heidelberg). ISBN: 978-3-540-88180-3.
[C20] S. Cimato, M. Gamassi, V. Piuri, R. Sassi, F. Scotti, Privacy-Aware Biometrics: Design and Implementation of a
Multimodal Verification System, in Annual Computer Security Applications Conference, 2008. ACSAC 2008, Anaheim,
California, USA. December 8–12, 2008, pp. 130-139, IEEE Computer Society Press. ISBN: 978-0-7695-3447-3
[C19] L. T. Mainardi, M Bertinelli and R. Sassi, Analysis of T-wave alternans using the Ramanujan transform, in
Computers in Cardiology, Bologna, Italy, 14-17 September 2008, vol. 35, pp. 605-608. ISSN: 0276-6574. ISBN: 978-1-
4244-3706-1.
[C18] R. Sassi and L. T. Mainardi, Editing RR series and computation of long-term scaling parameters, in Computers
in Cardiology, Bologna, Italy, 14-17 September 2008, vol. 35, pp. 565-568. ISSN: 0276-6574. ISBN: 978-1-4244-3706-1.
[C17] A. Azzini, S. Marrara, R. Sassi, and F. Scotti, A Fuzzy Approach to Multimodal Biometric Authentication, in
Knowledge-Based Intelligent Information and Engineering Systems, 11th International Conference, KES 2007, XVII
Italian Workshop on Neural Networks, Vietri sul Mare, Italy, September 12-14, 2007. Proceedings, Part II. (Bruno
Apolloni, Robert J. Howlett, Lakhmi C. Jain, ed.), vol. 4693 of Lecture Notes in Computer Science, pp. 801-808,
Springer. ISBN: 978-3-540-74826-7.
[C16] S. Cimato, M. Gamassi, V. Piuri, R. Sassi, and F. Scotti, A biometric verification system addressing privacy
concerns, in Computational Intelligence and Security, 2007 International Conference on, pp. 594-598, IEEE Computer
Society Press, Harbin, China, 15-19 December 2007. ISBN: 978-0-7695-2823-6
[C15] R. Sassi, V. D. A. Corino, and L. T. Mainardi, Analysis of surface atrial signals using spectral methods for time
series with missing data, in Computers in Cardiology, vol. 34, pp. 153-156, Durham (NC), USA, 30 September-3
October 2007. ISSN: 0276-6574. ISBN: 978-1-4244-2533-4.
[C14] S. Cimato, M. Gamassi, V. Piuri, D. Sana, R. Sassi, and F. Scotti, Personal identification and verification using
multimodal biometric data, in Proceedings of the 2006 IEEE International Conference on Computational Intelligence
for Homeland Security and Personal Safety, pp. 41-45, IEEE Computer Society Press, Alexandria (VA) USA, 16-17
October 2006. ISBN: 1-4244-0745-1.
[C13] D.A. Tironi, R. Sassi, L.T. Mainardi, “Automated QT Interval Analysis on Diagnostic Electrocardiograms”,
Computers in Cardiology 2006, Valencia, Spain, vol. 33, 353-356 (IEEE Computer Society Press, NY, 2006). ISSN:
0276-6574. ISBN: 978-1-4244-2532-7.
[C12] V.D.A. Corino, F. Ziglio, F. Lombardi, R. Sassi, L.T. Mainardi, “Analysis of Atrial Signal during Adrenergic
Activation in Atrial Fibrillation”, Computers in Cardiology 2006, Valencia, Spain, vol. 33, 141-144 (IEEE Computer
Society Press, NY, 2006). ISSN: 0276-6574. ISBN: 978-1-4244-2532-7.
[C11] R. Sassi, L.T. Mainardi, P. Maison-Blanche, S. Cerutti. “Estimation of spectral parameters of residual ECG signal
during atrial fibrillation using autoregressive models”. Folia Cardiologica. (2005) vol. 12, supl. C, pp. 108-110. ISSN:
1507-4145. Special Issue: Proc. of the joint ISHNE and ISE Congress.
[C10] LT Mainardi, R Sassi, “Analysis of Scaling Behaviour of ECG Signal during Atrial Fibrillation”, Computers in
Cardiology 2005, Lyon, France, vol. 32, 627-630 (IEEE Computer Society Press, NY, 2005). ISBN: 0-7803-9337-6.
[C9] R Maestri, GD Pinna, P Allegrini, R Balocchi, A Casaleggio, G D'Addio, M Ferrario, D Menicucci, A Porta, R
Sassi
, MG Signorini, MT La Rovere, S Cerutti, “Linear and Non-Linear Indices of Heart Rate Variability in Chronic
Heart Failure: Mutual Interrelationships and Prognostic Value”, Computers in Cardiology 2005, Lyon, France, vol. 32,
981-984 (IEEE Computer Society Press, NY, 2005). ISSN: 0276-6574. ISBN: 0-7803-9337-6.
[C8] M. Ferrario, M.G. Signorini, R. Sassi, S. Cerutti, “Multiscale entropy analysis of 24 hours heart rate variability
time series”, MEDICON and HEALTH TELEMATICS 2004, “X Mediterranean Conference on Medical and Biological
Engineering”, Ischia (Naples), Italy, IFMBE Proceedings 2004, vol. 6, 4 pages. ISBN: 88-7780-308-8.
[C7] L.T. Mainardi, M. Matteucci, R. Sassi, “On Predicting The Spontaneous Termination Of Atrial Fibrillation
Episodes Using Linear And Non-Linear Parameters Of ECG Signal And RR Series”, Computers in Cardiology 2004,
Chicago (IL), USA, vol. 31, pp 665-668 (IEEE Computer Society Press, NY, 2004). ISSN: 0276-6574. ISBN: 0-7803-
8927-1.
[C6] M.G. Signorini, R. Sassi, S. Cerutti, “Working on the NOLTISALIS Database: measurement of nonlinear
properties in heart rate variability signals”, Proc. of the IEEE-EMBS Conference, Istanbul, Turkey, 2001, pp547-550
(IEEE Press, Piscataway, NJ, USA). ISBN: 0-7803-7211-5. ISSN: 1094-687X.
[C5] G. Magenes, M.G. Signorini, R. Sassi, “Automatic diagnosis of fetal heart rate : comparison of different
methodological approaches”, Proc. of the IEEE-EMBS Conference, Istanbul, Turkey, 2001, pp 1604-1607 (IEEE Press,
Piscataway, NJ, USA). ISBN: 0-7803-7211-5. ISSN: 1094-687X.
[C4] G. Magenes, M.G. Signorini, R. Sassi, D. Arduini, , “Multiparametric analysis of fetal heart rate: comparison of
neural and statistical classifiers”, MEDICON 2001 - IX Mediterranean Conference on Medical and Biological
Engineering and Computing, IFMBE Proceedings, Pula, Croatia, 2001 Part I, pp 360-363. ISBN: 953-184-023-7.
[C3] M.G. Signorini, A. de Angelis, G. Magenes, R. Sassi, D. Arduini, S. Cerutti, “Classification of fetal pathologies
through fuzzy inference systems based on a multiparametric analysis of fetal heart rate”, Computers in Cardiology
2000, Cambridge (MA), USA, pp 435-438 (IEEE Computer Society Press, NY, 2000). ISSN: 0276-6574. ISBN: 0-7803-
6557-7.

[C2] M.G. Signorini, M. Calò, R. Sassi, S. Guzzetti, S. Cerutti “Nonlinear analysis of heart rate variability signal in
heart transplanted subjects: bicaval vs standard orthotopic techniques”, Proc. of the joint BSI IEEE-EMBS Conference,
Chicago, 2000 (CD-Rom, IEEE Press, Piscataway, NJ, USA, 20 pages). ISSN: 1094-687X.
[C1] Maria G. Signorini, Roberto Sassi, Federico Lombardi, Sergio Cerutti, “Regularity patterns in heart rate
variability signal: the approximate entropy approach” Proceedings of IEEE-EMBS Conference, Hong Kong, 1998, pp
306-309 (IEEE Press, Piscataway, NJ, USA). ISBN: 0-7803-5164-9. ISSN: 1094-687X.
D. Patents
[D2] S. Cimato, M. Gamassi, V. Piuti, D. Sana, R Sassi, F. Scotti, Publication number WO/2007/113888: "Method
for generating and verifying security information obtained by means of biometric readings". Deposited: 29
March 2007. Property: Università degli Studi di Milano. [PCT extension of the MI2006A000641 patent:
PCT/IT2007/000235]
[D1] S. Cimato, M. Gamassi, V. Piuri, D. Sana, R. Sassi, and F. Scotti, Patent number MI2006A000641: "Metodo
di generazione e di verifica di una informazione di sicurezza ottenuta mediante letture biometriche".
Deposited: 31 March 2006. Property: Università degli Studi di Milano
E. Technical reports and others publications
[E3] R. V. Craster, R. Sassi, “Spectral algorithms for reaction-diffusion equations”, Note del Polo – Ricerca N.99,
Technical Report, Università di Milano, Polo di Ricerca di Crema, 2006.
[E2] S. Cimato, M. Gamassi, V. Piuri, R. Sassi, and F. Scotti, Privacy issues in biometric identification, 2006. Nigel
Llyod ed., Touch Briefings, ISBN:1-905052-96-0.
[E1] R. Sassi, “Nonlinear coupled oscillators” in Woods Hole Oceanographic Institution Technical Report, WHOI-
2000-07, pp 141-166 (Woods Hole MA, 2000).

Source: http://www.dti.unimi.it/sassi/CV_eng.pdf

Document3

136 Drugs That Can Cause Cognitive Impairment http://www.worstpills.org/includes/page.cfm?op_id=458 /Home/Alzheimer's Treatments/ Medicines to Avoid for Alzheimer's Patients Drug-induced dementia and delirium are commonly misattributed to underlying medical illness or merely to "old age." But patients (and even their doctors!) might not know that by stopping or modifying the dosage o

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