BELLEVUE MEDICAL PARTNERS PLLC Spring 2008
1750 112th Ave NE Bellevue, WA 98004 (425)637-1022
INSIDE THIS ISSUECholesterol medication in the news
At the recent American College of Cardiology
conference, results of a trial were released
which showed no benefit with Ezetimide by
itself (Zetia) or with Simvastatin (Vytorin) in
stopping plaque progression in a very high
risk population of people. For those who
diligently read these newsletters, this is
nothing new. In our winter 2007 newsletter,
cholesterol down low enough does in fact slow
we briefly reviewed this study. It showed
and even stop the progression of cholesterol
cholesterol treated with Vytorin or Zetia,
medicines are useful tools in helping to
plaque continued to grow. This was widely
achieve those targets. The result is that there
publicized as proof that the medicine was
ineffective and shouldn’t be used. Looking
regarding cholesterol treatment at this time.
more carefully at the data shows that the
cholesterol was so high that these medicines
by themselves did not get the cholesterol
down to the levels needed to stop plaque
from progressing. Therefore, these results
would be expected. There is a large body of evidence showing that getting the
throughout the medical community about these data
“A recent study looking at aggressive control of
and what they mean for diabetic care. Moreover, the
diabetes found an increase risk of cardiac death in
theories behind diabetic care are being called into
patients with poorly controlled diabetes who were
question. While many are worried, we find this
treated aggressively (HgA1c< 6.5) versus a group
refreshing! It is the nature of medical science to
that were managed to an appropriate but less
question everything in an attempt to fully understand
aggressive goal (HgA1c < 7.0). At the same time,
how our bodies work and how to treat when things go
another study showed an overall 20% reduction in
wrong. Even a disease like diabetes where treatment
death from any cause in a group of diabetics treated
seems straight forward – get the sugar back to normal
to the more aggressive goal. While the studies
– is not above the questioning process. Indeed, the
disagree about the effects of aggressive diabetes
system is working! To date there has been no
management on death rates, they agree on the fact
recommendation to change the way we treat diabetes
that treating diabetes to the more aggressive goal
and there will be much discussion and further studies
of HgA1c < 6.5% reduces many of the other
attempting to clarify these issues. We will be studying
complications of diabetes such a nerve, kidney and
this data carefully as it emerges and plan on staying
You may have noticed that over the past 2 years we have started checking vitamin D levelsperiodically. Traditionally, vitamin D has been viewed as important for bone health. Recently, there is evidence that vitamin D may be associated with lower rates of several types of cancer
summer, the use of sunscreen effectively blocks
including colon, breast, ovarian and prostate
cancer. It is not yet proven whether normal vitamin D levels prevent these cancers or whether
It is nationally recommended that we get 400
there is another explanation for this observation.
units daily of vitamin D. We recommend at least
Similarly, adequate vitamin D is associated with a
800 units daily and more if you are deficient. In
decreased risk of developing diabetes, reduction
the last few moths, vitamin D has drawn the
in systemic inflammation that accelerates
attention of the media and you will be hearing
atherosclerosis and enhances the immune system.
more about this in news reports and articles.
Vitamin K is largely manufactured in the skin when
We will continue to monitor information as it
we are exposed to sunlight. A 15 minute exposure
is all that is needed to meet the body’s
discuss any questions you have when you are in
requirements. In Seattle, we have less sun
exposure through the winter months and in the
Wedding bells are ringing! Dr Kaner has been busy writing checks and flying to California in preparation for his eldest son’s July wedding.
Ali was recently engaged to be married! Plans are
for a spring 2009 wedding in Hawaii.
Acta Poloniae Pharmaceutica ñ Drug Research, Vol. 68 No. 2 pp. 291ñ294, 2011HYPOLIPIDEMIC EFFECT OF FRESH TRITICUM AESTIVUM (Wheat) GRASSSAROJ KOTHARI*, ANAND K. JAIN, SWAROOP C. MEHTA and SHRINIVAS D. TONPAYDepartment of Pharmacology, Gajara Raja Medical College, Gwalior, M.P., India Abstract: Present study was aimed to elucidate hypolipidemic effect of fresh Triticum aestivum (common
HEALTH INNOVATION SYSTEMS IN DEVELOPING COUNTRIES Strategies for Building Scientific and Technological Capacities John Mugabe NEPAD Office of Science and Technology WORKING DRAFT Health Innovation Capacities of Developing Countries INTRODUCTION There is a growing recognition that the extent to which developing countries will be able to reduce the burden of disease an