Es ist nicht klar, wie groß die Rolle von Antibiotika https://antibiotika-wiki.de/ in den Wettbewerbsbeziehungen zwischen Mikroorganismen unter natürlichen Bedingungen ist. Zelman vaxman glaubte, dass diese Rolle minimal ist, Antibiotika werden nicht anders als in reinen Kulturen auf reichen Umgebungen gebildet. Anschließend wurde jedoch festgestellt, dass bei vielen Produzenten die Aktivität der antibiotikasynthese in Gegenwart anderer Arten oder spezifischer Produkte Ihres Stoffwechsels zunimmt.

Cannonsitecarecard(revised)

CannonSiteCareCard(revised) 6/24/04 9:35 AM Page 1 Arrow® Cannon Catheter™ Site Care
The Arrow® Cannon Catheter™ II and Cannon™ II Plus catheters are constructed of different radiopaque polyurethane materials and therefore require
separate site care details. Warning: Prior to catheter and skin prep, refer to appropriate Site Care sections to identify indwelling catheter body type.
Site Care for Cannon™ II Plus Catheter**
Site Care for Cannon Catheter™ II
1. Alcohol, alcohol-based solutions (e.g. Hibiclens®, ChloraPrep®),
1. IODINE-based solutions (e.g. Povidine-iodine), commercially
iodine-based solutions (e.g. Povidine-Iodine), mineral oil-based available ExSept® are recommended as antiseptic solutions that ointments, hydrogen peroxide or commercially available ExSept® are accepted for use with this catheter.
is accepted for use with this catheter.
2. Mineral oil-based ointments are acceptable.
2. Ensure that solution is completely dry before applying an
3. Avoid use of alcohol, alcohol-based solutions (e.g. Hibiclens®,
ChloraPrep®) acetone, or hydrogen peroxide to clean catheter or 3. Avoid excessive or prolonged use of alcohol-based solutions
site care as this causes catheter degradation and failure may occur.
and ointments to clean catheter or site care.
4. Do not use any type of solvent to clean catheter or extension
4. Do not use acetone with this catheter, catheter degradation may occur.
lines. Catheter degradation and failure will occur.
5. Avoid use of ointments containing Polyethylene Glycol (PEG)
5. Avoid use of ointments containing Polyethylene Glycol (PEG)
on this catheter, with the exception of Bactroban®.
6. Clean skin around catheter using accepted solution antiseptics.
6. Clean skin around catheter using iodine-based antiseptics. Cover
Cover exit site care with sterile occlusive dressing for the entire exit site with sterile occlusive dressing for the entire duration of duration of implantation. If catheter swelling is observed, implantation. If catheter swelling is observed, discontinue use discontinue use and replace catheter.
• Wound dressings must be kept clean and dry. Caution: Patients must not swim, shower, or soak dressing while bathing. • If excessive perspiration or accidental wetting compromises adhesion of dressing, medical or nursing staff must change dressing Heparinization: To maintain patency of catheter between treatments, a heparin-lock must be created in each lumen of catheter.
Concentration of heparin used should be determined by hospital protocol. If catheter is not going to be used, it is recommended that catheter
be flushed and re-packed with heparin every 48-72 hours.
MR Environment: This device presents no additional risks to the patient or other individuals during use with shielded magnetic
resonance (MR) systems up to 3.0-Tesla, but may produce some MR imaging artifact in the area of the device. More detailed information
regarding the use of this device in an MR environment is available upon request.
CannonSiteCareCard(revised) 6/24/04 9:35 AM Page 2 Arrow® Cannon Catheter™ Site Care
Compatibility Of Site Care Antiseptics1
Antiseptic Agents
Cannon™ II Plus+, ¥
Cannon Catheter™ II+
References:
1. In-vitro test data available upon request.
2. Centers for Disease Control and Prevention “Guidelines for the Prevention of Intravascular
Catheter-Related Infections,” August 9, 2002, Volume 51.
3. National Kidney Foundation. NKF-K/DOQI Clinical Practice Guidelines for Vascular Access: update 2000. AmJ Kidney Dis 2001; 37 (supl): S137-S81.
¥ Carbothane™ is a trademark of Noveon IP Holding Corp.
Caution: U.S. Federal law limits this device to sale by or on order of a physician.
Bactroban® is a registered trademark of Smithkline Beecham Corporation.
Contents of unopened, undamaged package are sterile. Disposable. Refer to ChloraPrep® is a registered trademark of Medi-Flex Hospital Products Corporation.
package insert for current warnings, precautions, and instructions for use. ExSept® is a registered trademark of Double Diamond Partners LLC.
Contact Arrow International, Inc. for reference information on the above.
Hibiclens® is a registered trademark of Zeneca Limited Corporation.
CAN II-M 03/04 10M 2004 Arrow International, Inc. All rights reserved. Printed in the U.S.A.

Source: http://www.arrowintl.com/documents/pdf/literature/canii-m0304.pdf

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