Inhaled QUICK RELIEF Medications Generic Name Brand Name Strengths (# Doses/Inhaler) Comments Short-Acting Beta2-Agonists
Pre-mixed unit dose (3 mL); vials must be placed back in the foil wrap after the foil wrap is
opening; expires 1 week after foil wrap is opened
Albuterol for Nebulization
0.25-0.5 mL can be added to 2-3 mL saline
Supplied as 20 mL dropper bottle; must use dropper provided to measure up dose.
MDI; should be used with a spacer; shake 5 seconds; 3 primes to start; reprime after 2 weeks
ProAir HFA Albuterol Proventil HFA,
MDI; Ventolin has a dose counter; should be used with a spacer; shake 5 seconds; 4 primes to
Ventolin HFA
start; reprime after 2 weeks without use or if dropped; expires 6 months after opening
MDI; should be used with a spacer; shake 5 seconds; 4 primes to start; reprime after 3 days
Xopenex HFA Levalbuterol Xopenex Nebulized
Unit dose for nebulization; needs no mixing; must use as soon as foil wrapper is opened
Maxair Autohaler
MDI; breath-actuated so no spacer needed; shake 5 seconds; 2 primes to start; reprime after 2
Pirbuterol MDI, metered dose inhaler; CFC, chlorofluorocarbon propellants; HFA, hydrofluoroalkane propellants
The information in this reference was reviewed by the UMHS Asthma Quality Improvement Steering Committee and was last updated on 1/31/2011.
Questions and/or comments may be directed to Karla Stoermer-Grossman, MSA, RN, AE-C (kstoerme@umich.edu) or Annie Sy, PharmD (anniesy@umich.edu).
The Regents of the University of Michigan – January 2011
Inhaled CONTROLLER Medications Generic Name Brand Name Strengths (# Doses/Inhaler) Comments Inhaled Corticosteroids (ICS)
MDI; should be used with a spacer; no shaking required; 3 primes to start; reprime after 10
Ciclesonide Alvesco HFA
days without use; dose indicator in increments of 10
110 mcg per actuation (14, 30, 60, or 120)
Has dose counter; no priming; do not tip once dose is loaded; avoid humidity & moisture; may
Mometasone Asmanex DPI*
220 mcg per actuation (14, 30, 60, or 120)
be given once daily in the evening; expires 45 days after opening
Has dose counter; no priming; do not tip once dose is loaded; avoid humidity and moisture; 50
Flovent DPI*
mcg strength is equivalent to Flovent HFA 44 mcg; expires 6 weeks after opening.
Fluticasone
MDI; has dose counter; should be used with a spacer; shake 5 seconds; 4 primes to start;
Flovent HFA+
reprime after 7 days without use or if dropped
Pulmicort Flexhaler
Has dose indicator in increments of 10; must twist fully to the right, then left twice to prime;
do not tip once dose is loaded; avoid humidity and moisture
Budesonide
Deliver with closed system mask if < 3 years (Bubbles fish mask); older children may use a
Pulmicort Respules
12 months to 0.25, 0.5 or 1.0 mg per unit dose
mouthpiece if they are able to breath through their mouths only (nose clips may be helpful);
Budesonide (generic)
MDI; adults - recommended to be used without spacer; peds- may use with spacer; no shaking
Beclomethasone
required; 2 primes to start; reprime after 10 days without use
Long-Acting Beta2-Agonists (LABAs) - NOT TO BE USED WITHOUT ICS Not to be used for quick relief or without ICS in asthma; has dose counter; no priming; do not Salmeterol Serevent DPI*
tip once dose is loaded; avoid humidity and moisture; expires 6 weeks after opened; expires 6 weeks after opening
Not to be used for quick relief or without ICS in asthma; sometimes used for exercise-induced Formoterol Foradil DPI*
bronchospasm prevention; no priming; do not tip once dose is loaded; avoid humidity and moisture; expires 4 months after opening
ICS and LABA Combinations
No priming; has dose counter; do not tip once dose is loaded; avoid humidity and moisture; do
Advair DPI*
100/50, 250/50 or 500/50 mcg per inhalation (60)
not use more than one dose twice daily; expires 1 month after opening
Fluticasone and Salmeterol
45/21, 115/21 or 230/21 mcg per inhalation
MDI; has dose counter; should be used with a spacer; shake 5 seconds; 4 primes to start;
Advair HFA
reprime after 4 weeks without use or if dropped; do not use more than twice daily
MDI; should be used with a spacer; shake 5 seconds; 4 primes to start, reprime with 4 puffs
Mometasone and
after 5 days without use; do not use more than twice daily; do not remove cannister from the
Formoterol
MDI; has dose counter; should be used with a spacer; shake 5 seconds; 2 primes to start,
Budesonide and Symbicort HFA
80/4.5 or 160/4.5 mcg per inhalation (120)
reprime after 7 days without use; do not use more than twice daily; expires 90 days after
Formoterol
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